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STR

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STR STR (short tandem repeat ... – PowerPoint PPT presentation

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Title: STR


1
STR
?
??????? ???????
2
STR ???????(short tandem repeat )
  • ?????????????????????,STR
    ?????????26bp , ????1060 ?,?????100500bp ??,
    ?????????????

3
  • STR????????,??610kbp ?????,???????????????????
    ????????????, ???STR ???????

4
  • ? Gene Bank ????????, ??23 ??????????7901?STR??
    , ??????????????264???, ?????STR ??????,
    ?????????, ???????????STR , ??????????

5
STR ?????
  • ????????????????
  • ???????????
  • ????????????????
  • ??????????

6
????????????????
  • ???????????? (Human Genome Project,
    HGP) ????????????????, ???????????????DNA
    ????????

7
STR ???????????
  • ????????????, ?????STR ?????????
  • ?????????
  • ????????????STR ???, ????????????
  • ???????, ?PCR ??, ??????, ?????????

8
  • ???????(Single nucleotide polymorphism, SN P)
    ?????????????, ??STR ??????????,????SN P
    ???????STR??

9
  • ????SN P ????????????STR?20 30 ,
    ??????????SN P ???????????STR ???????STR
    ???????????, ????????????

10
???????????
  • 1??????
  • 2?????????????
  • 3 ??????????

11
1 ?????
  • ????????????????????????????????????????STR????
    ??, ??????????, ???????STR ????, ??????????????1
    3 cm ????

12
  • ?? STR ????????????????????????????????????,
    ????????????????, ??????????????????????

13
2 ????????????
  • ??????, STR ??????????????????????,
    ?????????????, ????????????????????????????????Hun
    tington ??Kennedy ????X ?????

14
3 ?????????
  • ??, ??????????????????,??????????????,
    ??????????????????????????????????STR
    ??????????????????????

15
????????????????
  • STR ?????????, ???????????????,
    ?????????????????, ???????????????, ??????????STR
    ???, ???????????????????, ????????????,
    ?????????????????????????????

16
??????????
  • ???90 ????, ?????????????,
    ??????????5?STR ????????75 ???????????, ?DNA
    ????50 pg ???????, ???9 ????????????

17
  • ??, ??DNA ???????, STR
    ????????????????????????,?????????????????????????
    ??????????????????

18
STR ???????
  • STR?????????????????????STR
    ??????????????????????????????????, ????AT ?STR
    ?????STR ?????????, ????????????????????

19
STR ?????
  • STR ?????????STR ???????????????????????
    ?????????? STR ??????????, ??????????

20
Thanks!
21
????
  • ??????????????,??? ?? ???,????????
    2005Jun22(3
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