ETPGAH UK Mirror Group

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ETPGAH UK Mirror Group

• Progress report

Phil Sketchley - Chief Executive National Office
of Animal Health Ltd
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UK Mirror Group

• Structure and functioning (stakeholders, chair,
  secretariat, meetings, etc.)
• Action plan and selection of priorities
• Communication at national level
• Directing national funding
• Work programme for 2008

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Structure of UK Mirror Group

• Secretariat VMD (Veterinary Medicines
  Directorate)
• Professor Steve Dean Chief Executive
• Dr Jack Kay VMD-RD and Science Policy Manager
• Gemma Adams secretary
• Chair Phil Sketchley - NOAH National Office of
  Animal Health representing UK animal medicines
  industry.
• Current stakeholders
• Professor Quintin McKellar - Dean RVC- Royal Vet
  College
• Professor Julie FitzPatrick - Chief Executive,
  Moredun Research Institute.
• Dr John Preston MRCVS VMD Board.
• Catherine McLaughlin Animal Health and Welfare,
  National Farmers Union,
• Dr Alex Morrow Defra Animal Health and Welfare
  and Eurogap.
• Professor Jim Scudamore Liverpool Vet School
  ETPGAH consultant.
• Invitation to CVO (vacant)

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Progress of UK Mirror Group

• 2 meetings held so far hosted by Defra
• July 2007 and Jan 2008
• Key Actions _at_ first meeting
• ESTABLISHING GAPS in Research
• To assist in developing a common priority list,
  it was agreed each member would submit details of
  their perceived priorities
• 7 most important exotic diseases
• 7 most important endemic diseases
• 7 most important zoonotic diseases
• 7 most important products for treatment
• 7 most important areas for further research

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Exotic Diseases Priorities
Disease UK groups with
expertise

• Veterinary Laboratories Agency
• Institute for Animal Health, Compton Centre for
  Infections,
• Health Protection Agency
• Institute for Animal Health, Pirbright
• Institute for Animal Health, Pirbright
• Veterinary Laboratories Agency
• Scottish Agricultural College

• Avian influenza
• Foot and Mouth
• Blue tongue disease
• Newcastle disease

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Endemic Diseases Priorities
Disease UK groups with
expertise

• Mastitis (multi-agent)
• Tuberculosis (and diagnostic tuberculins)
• Parasitic gastroenteritis
• Lameness

• University of Bristol
• Veterinary Laboratories Agency, Moredun,
• AFBI Stormont,
• Imperial College
• Institute for Animal Health, Compton
• Moredun Research Institute
• University of Bristol
• Royal Veterinary College
• University of Liverpool
• Scottish Agricultural College
• University of Bristol

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Zoonotic Disease Priorities
Disease UK groups with
expertise

• Veterinary Laboratories Agency
• Health Protection Agency
• University of Edinburgh
• Imperial College
• Veterinary Laboratories Agency,
• Institute for Animal Health, Compton
• University of Bristol
• University of Cambridge
• University of Nottingham University of Oxford
• Veterinary Laboratories Agency,
• Institute for Animal Health, Compton
• Institute of Food Research, Norwich
• University of Bristol
• University of Cambridge
• University of Nottingham
• Veterinary Laboratories Agency

• VTEC 0157
• Campylobacter
• Salmonella
• Antimicrobial resistance

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Summary
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Others?

• Toxoplasmosis
• Sheep scab
• African Swine Fever
• Bovine viral diarrhoea
• Porcine reproductive and respiratory syndrome
• Tick-borne diseases
• Necrotic enteritis
• Infectious bronchitis
• Gumboro Mareks
• Brachyspira
• Neospora

• West Nile Fever
• Echinococcus multilocularis
• Classical swine fever
• African Horse Sickness
• Leishmaniasis (via PETS)
• Heartworm (dirofilaria immitis)
• Fascioloiasis
• Anthrax
• Cryptosporidiosis
• Toxoplasmosis
• Leptospirosis

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ANNEX ADDITIONAL DISEASES AND ISSUES OF
IMPORTANCE TO UK TO BE KEPT UNDER REVIEW

• Cat Flu (emerging virulent strains and novel
  approaches to control)
• Borders disease
• Strangles
• Feline Immunodeficiency Virus
• Mycoplasma
• Feline Infectious Peritonitis
• Myxomatosis
• Angiostrongylus vasorum
• E. Cuniculli
• Pasterellosis (rabbits)

• Rabies
• Nosema ceranae infestation
• Equine protozoal myeloencephalitis
• Porcine Multisystemic Wasting disease (PMWS) pigs
• Transmissable Spongiform Encephalopathies
• Caseous Lymphadenitis (sheep)
• Clostridium botulinum

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ANNEX ADDITIONAL DISEASES AND ISSUES OF
IMPORTANCE TO UK TO BE KEPT UNDER REVIEW

• Infectious pancreatic disease (IPN) salmon
• Bovine abortion
• Bovine respiratory disease
• Swine respiratory disease
• Poultry coccidiosis/ colisepticaemia
• Varroa destructor infestation
• Digitial Dermatitis
• Neopspora vaccine
• Anthelmintic resistance (sheep mainly)
• Caseous Lymphadenitis (sheep)

• RabiesOrf/ringworm
• Listeriosis
• Lyme Borreliosis
• Blackhead (turkeys)
• Bee products Small Hive Beetle, etc.
• Anticancer medicines for companion animals
• Antibiotic to treat nosema (both apis and ceranae
  forms)
• Fish infectious diseases and issues (e.g. ERM,
  PKD, sea lice)

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ANNEX ADDITIONAL DISEASES AND ISSUES OF
IMPORTANCE TO UK TO BE KEPT UNDER REVIEW

• Anthelmintics (new mode of action chemical family
  and vaccines)
• Alternatives to animal challenge tests for
  vaccines
• DIVA vaccines
• Risk based methodology for re-testing veterinary
  vaccines
• DNA vaccines
• Coccidiosis
• Chlamydiosis
• Equine viruses
• Brucellosis
• Ruminant respiratory viruses
• TSEs

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Centres of expertise for collaboration with UK
Mirror Group-summary

• Institute for Animal Health (Pirbright) - FMD,
  Bluetongue
• Institute for Animal Health (Compton) -
  Salmonella, Campylobacter, Mareks Disease,
  Coccidiosis
• VLA (veterinary Laboratories Agency) - TB,
  Rabies, AI
• Moredun - Parasitic gastroenteritis,
  Chlamydiosis, ParaTB
• University of Bristol - Campylobacter, Salmonella
• University of Cambridge - Salmonella,
  Campylobacter
• RVC - influenza (epi), Lameness, Antimicrobial
  resistance.
• AHT (Animal Health Trust) - equine viruses
• Stormont - Brucellosis, ruminant respiratory
  viruses

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Communication at national level

• So far just within immediate group
• Now we intend to embrace a larger audience of
  research establishments

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Directing national funding

• No specific actions initiated yet.
• This will be addressed at our next meeting in
  April
• Also to determine a detailed work programme after
  identifying collaboration with other national
  mirror groups

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ETPGAH
UK Mirror Group