The Needle in a Haystack: Hereditary Angioedema

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The Needle in a Haystack Hereditary Angioedema
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What Is HAE?
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Epidemiology of HAE
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Autosomal-Dominant Inheritance
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C1-INH Mutations
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Function of C1-INH
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Nikki Introduction of Patient
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Nikkis Angioedema Attacks
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Nikki Follow-up
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Clinical Presentation of Angioedema
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Differential Diagnosis of Angioedema
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Bradykinin- vs Histamine-Mediated Angioedema
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Onset and Location of HAE Symptoms
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Delay in HAE Diagnosis
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Nikkis Laboratory Results
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Nikki Sees an HAE Specialist
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Angioedema of Unknown Etiology
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Algorithm for Diagnosis of HAE
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Importance of Early Recognition and Screening
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Categories of HAE Treatment
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Therapies for HAE
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Recommendations for Treatment of Acute Attacks of
HAE
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FDA-Approved Therapies for Acute Treatment
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Recommendations for Use of Prophylactic
Management of HAE
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Commonly Used Prophylactic Therapies
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Case 2 Patient With a Diagnosis of HAE
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Case 2 (cont)
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Patient Case 3 Treatment Plan in 11-Year-Old Boy
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Case 4 Use of ARBs
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Abbreviations
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References
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References (cont)
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References (cont)