Krebs Cycle

1
Krebs Cycle

• Asya Mamaev
• Ib1 Biology

2
Anaerobic and aerobic respiration
Aerobic- with oxygen
Aerobic- occurs in the mitochondrion
Anaerobic- without oxygen

• Glycolosis can occur without oxygen
• The basis of anaerobic cell respiration

3
The link reaction
Decarboxylation- Removal of carbon dioxide
NAD
NADH H
Pyruvate from glycolysis is absorbed by the
mitochondrion
Acetyl CoA
pyruvate
CoA
CO2
Enzymes in the matrix of the mitochondrion remove
hydrogen and carbon dioxide from the pyruvate

• The hydrogen is accepted by NAD.
• This is oxidation

4
The Krebs Cycle
CoA

• Acetyl group is transferred from acetyl CoA to a
  four-carbon compound to form a six-carbon compound

oxoaloacetate
citrate
NAD
FAD
ADP
Krebs Cycle
5
Vocabulary
pages

• Link reaction
• Krebs cycle
• Oxidative decarboxylation
• Decarboxylations
• Oxidations
• Substrate-level phosphorylation

Study guide page 74