?????????? (Hypoxic-Ischemic Encephalopathy, HIE ) (Hypoxic-Ischemic Brain Damage, HIBD) ??????? ? ? ? - PowerPoint PPT Presentation

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?????????? (Hypoxic-Ischemic Encephalopathy, HIE ) (Hypoxic-Ischemic Brain Damage, HIBD) ??????? ? ? ?

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Hypoxic-Ischemic Encephalopathy, HIE ) (Hypoxic-Ischemic Brain Damage, HIBD) – PowerPoint PPT presentation

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Title: ?????????? (Hypoxic-Ischemic Encephalopathy, HIE ) (Hypoxic-Ischemic Brain Damage, HIBD) ??????? ? ? ?


1
??????????(Hypoxic-Ischemic Encephalopathy, HIE
) (Hypoxic-Ischemic Brain Damage,
HIBD)???????? ? ?
2
????????????????????????????????????
?????????????????
??
3
???
??? 0.2-0.4 ??? 60
??
25??? ???
10 - 60 ??????
4
???????????????A. ????? 20
?????????????????? ??????B. ????? 70
????????????????C. ????? 10
RDS????????
??
??
5
???(CBF)?? ???????????????????? ??????
???????????????? ??????
????
6
????? ?O2???????,??????,
ATP???? ATP??,Na?Ca2 ?????, Na?
Ca2?? ATP ???? ??????
????????,??Na?Ca2 , ??????????
??
???
7

????
?? ??? ???? ?? ????? ?? ?????
??
??
??
8
??
24h?????? ????????? ?????
9
24h - 72h??????,
?????????? ?50???? ??48-72h???
?? ????? ???????
??
10
????????????? ?????
??12h?????,??????? ????????? ????
???????,????????? ?,????????????
??
11
????lt5???,???? ?? gt7d,???????
? ?
12
??
????
????
??
13
?? ??????? Apgar?? 1??lt3' 5??lt5'
?????????pH 7.00
14
???? ??12h?????????
???
??
??
??
15
????
????
HIE???? (72???) ???? ???????
?????????????? ???????
16
(No Transcript)
17
(No Transcript)
18
(No Transcript)
19
(No Transcript)
20
??CT
  • ??4-7???
  • ????
  • ??????????????????
  • ???????????????????
  • ??
  • ????3-4?????

21
(No Transcript)
22
(No Transcript)
23
(No Transcript)
24
??MRI
?HIE?????????????CT ???? T1WI ???? (DWI)
?????,???
25
(No Transcript)
26
???
??1???? ????????????????,?????????
(???????),?????? (???????????) ?????????????
(aEEG) ????
27
1. ?? 2. ???? 3. ???? 4. ????
? ?
????
28
1.???????,?????? 2.???????,????????
3.??????????????? ???????????????
???????????????? ?????????
??????
??????
29
????????,????????? 1.??????????????GM-1
2.????? 3.????????????,?????? ????????
??????
?????
30
? ?
  1. HIE??????????
  2. ??????HIE?
  3. HIE????
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