Progeria

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Progeria
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Alternative Names

• Hutchinson-Gilford Syndrome
• Hutchinson-Gilford Progeria
• Hutchinson-Gilford Disease
• Souques-Charcot syndrome

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Who is most likely to get Progeria?

• There is no way of knowing who will get Progeria,
  it is not passed down in families.
• 1 in 4-8 million get Progeria.
• It is rare that someone gets Progeria from a
  family member (1 in 400 million).
• Gender does not matter in Progeria any one could
  get it.

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Symptoms

• When the kids are born they all look the same.
• At about 18-24 months the symptoms start kicking
  in.
• The symptoms are
• - Growth failure
• - Lose of body fat and hair
• - Aged looking skin
• - Stiffness of joints
• - Hip dislocation
• - Cardiovascular Disease and stroke
• Progeria is caused by a mutation in the gene LMNA
  (Lamin). This gene produces A protein which holds
  the nucleus of the cell together.
• The Lamin that is defective makes the nucleus
  unstable.

What the nucleus looks like for a Progeria
patient. ?
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How common is Progeria?

• 1 in 4-8 million
• If contributed by a family member 1 in 400
  million.

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Is Progeria deadly?Can it shorten lifespan?

• Yes, Progeria can be deadly most children die
  from heart disease.
• The lifespan of someone who has Progeria averages
  about 13 but it ranges from 8 to 21.

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Can you be tested for Progeria?

• You can see when a child has the symptoms of
  Progeria at 18-24 months.
• Most people know what Progeria looks like so you
  dont really know until they start changing when
  they grow older.

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Is there a treatment for Progeria?

• There is no treatment for this disease, sadly all
  they can do is live with it.
• Physical Therapy can help lower the heart attacks
  that the patients have.
• Also physical therapy can help the joint
  stiffness.

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Are there any support groups?

• There are many support groups for Progeria.
• One popular group is
• http//www.progeriaresearch.org/

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Interesting Facts

• People with Progeria age 7 times faster then we
  do.
• Know number of kids with Progeria, 54 in 30
  countries.
• Have the mind of a 10 year old.

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Works Cited

• "Progeria Facts." Buzzle Web Portal Intelligent
  Life on the Web. 18 Oct. 2010. Web. 26 Jan. 2011.
  lthttp//www.buzzle.com/articles/progeria-facts.htm
  lgt.
• Online, Credit Card. "Progeria Research
  Foundation Progeria 101/FAQ." Progeria Research
  Foundation Home. Nov. 2008. Web. 26 Jan. 2011.
  lthttp//www.progeriaresearch.org/progeria_101.html
  gt.
• "Progeria - Symptoms, Diagnosis, Treatment of
  Progeria - NY Times Health Information." Health
  News - The New York Times. 2007. Web. 26 Jan.
  2011. lthttp//health.nytimes.com/health/guides/dis
  ease/progeria/overview.htmlgt.

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