IBD

1
IBD

• Ulcerative Colitis
• Crohns Disease

2
IBD

• Pathogenesis genetics environment
  (smoking,infection,drugs)
• UC bloody diarrhoea. Exacerbation
  remission-50/yr
• CD- more heterogenous abdo pain,diarrhoea,wt
  loss,malaise,fever. 80 require surgery

3
Diagnosis

• Colonoscopy unless presenting with severe
  disease.
• Terminal ileoscopy BaFT
• CT/MR/US/WBC scanning

4
Management

• 5ASAs steroids local/systemic
• Azathioprine- good. TPMT assay
• UC consider CyA/infliximab
• CD Mtx/infliximab
• The future newer biological therapies