ENDOCRINE FUNCTIONING

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ENDOCRINE FUNCTIONING

• If in doubt, blame it on a hormonal response!

Composed by Becky De Neve, R.N.
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Hormonal Adjustments

• Negative Feedback Loops What are they?
  
• Communicating to the nervous system and the
  check and balance of homeo- stasis functioning.

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Negative Feedback Examples

• The thyroid acts to increase the amount of
  calcium to the bone.
• The parathyroid gland responses the opposite.
• In the pancreas, what is the hormone that works
  opposite of insulins work?

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Highly Specialized Messengers

• A communication network delivering protein or
  steroid chemical messen- gers to a specific
  endocrine gland. And, then delivering its
  hormones to a target organ.

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Lets look at some of its functioning..
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Metabolic Processes

• Controlled by the Anterior Pituitary gland
  under the regulation of the hypothalamus.
• TSH (Thyroid-stimulating Hormone) Helps
  control heat and energy production in our body.

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Fluid Balances

• Posterior Pituitarys influence of ADH
  (Anti-diuretic Hormone)
• Keeps us in a hydrated state!

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• The Adrenals influence homeostasis of fluid
  balance by the use of Aldosterone that assists in
  the regulation of electro- lytes and blood
  pressure.

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Electrolyte Balances

• Parathyroid Glands - mobilizes calcium from the
  bone to the bloodstream.
• Formation of strong bones and teeth, aids in
  blood clotting, transmission of nerve impulses,
  especially CALCIUM and PHOSPHORUS.

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Growth and Reproductive Development

• Somatotropic (STH) and Growth Hormone (GH)
  Examples are Acromegaly
  (Giantism) and Dwarfism
• Responsible for height, body physique. And,
  any unusual physical characteristics, if abnormal
  levels exist. Regulated by the anterior
  pituitary gland.

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Oh, is that where I get my shapely curves from?
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Fighting Inflammation

• Adrenocorticotropic (ACTH)
• Cortisol is a natural anti-inflammatory. Our
  body produces about 5 mg. daily.
• When steroids, exogenous amounts, are taken for
  long periods of time in greater than 15 mg.s per
  day, they can cause immunosupression.

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Fight or Flight Reactions

• Epinephrine produced by the adrenals medulla and
  stimulated by the Sympathetic Nervous System
• Dilates coronary arteries blood flow to the
  muscles.
• Constricts peripheral renal vessels.
• Allows relaxation of the smooth muscles of the
  bronchioles, bladder, and GI tract.

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Yipes, Im out of here! Thanks to epinephrine.
It also increases my canine glucose levels to run
away!
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Shock

• Norepinephrine allows most blood vessels to
  CONSTRICT conserving the BP.

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Reproduction, lactation, and sexual maturation

• will be addressed in fourth quarter work.
• Lets now look at when there is to much
  stimulating or inhibiting of specific hormonal
  actions.