Announcements

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Announcements

• Exams-
• Extra Credit -
• Lab 5 - Lymphatic System

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Lecture Overview

• Lymphatic System and Components
• What is lymph and how does it travel?
• General Immune Reaction- Inflammation
• What is one function of the cells carried in
  lymph?
• Selected Topics in Immunity

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Lymphatic System

• Absorbs excess fluid from the tissues
• Returns this fluid to the circulatory system or
  the heart
• Additional function in Immunity

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Components of the Lymphatic System

• Lymph
• Lymphatic Tissue
• Lymphatic Vessels
• Thymus
• Bone Marrow
• Spleen

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Lymph

• Lymph
• The clear fluid absorbed by the lymphatic system

• Lymphatic Tissue
• Clusters of Lymphocytes and macrophages

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Lymphatic Tissue

• Malt (Mucosa Associated Lymphatic Tissue)
• Diffuse array of lymphocytes found along body
  passages in mucous membranes.
• Examples of malt lining of the stomach and
  respiratory tract
• Lymph nodules
• Dense clusters of Lymphocytes
• Transient pop up during infection

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Lymphatic Vessels

• Carry and Transport Lymph and proteins
• Similar Structure to veins
• Tunica Interna Thin inner lining and valves
• Tunica Media Elastic fibers and Smooth Muscle
• Tunica Externa Thin Outer Layer

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Lymphatic Filters

• Lymph Nodes- Screen and Filter Lymph for
  infectious particles
• Spleen- Screen and Filter Blood for old, dead
  cells and infectious particles

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• Subclavian
• 2 collecting Trunks
• 6 Lymphatic Trunks
• More Collecting Vessels
• Lymph Nodes
• Collecting Vessels
• Lymphatic Vessels

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Lymphatic Movement

• No pump
• Rhythmic contraction of the lymph vessels
• Skeletal Muscles
• How is backflow prevented?

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Immune Cell Generators

• Bone Marrow- Makes B- Cells
• Thymus- Makes T- Cells

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Thymus
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Break for Dynamic Human
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Inflammation

• Non-specific response to tissue trauma or
  infection

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4 signs of Inflammation
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4 signs of Inflammation

• Redness
• Swelling
• Heat
• Pain
• What