Judicious antibiotic use

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Judicious antibiotic use Antibiotic resistance

• Julie Funk, DVM, MS, PhD
• The Ohio State University

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What are antibiotics?

• Chemical substances
• Produced by microorganisms OR
• Manufactured synthetically
• Inhibit or kill other organisms
• Used to treat infections of humans, animals,
  plants

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What is antibiotic resistance?

• Ability of a microorganism to be unaffected by an
  antibiotic
• Not a residueor antibiotics in your meat!
• Can result in treatment failure

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Why do we care?

• Importance of treatment success for animal health
• Increased resistance may limit our ability to
  treat animal disease

Cough!
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Antibiotic resistance

• Public Health Implications
• Estimated to cost 0.15-3 billion yearly
• Human usage a predominant contributor
• BUT---what about non-human use?
• Veterinaryparticularly livestock
• Aquaculture
• Horticulture
• Household

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AR as a Public Health Risk

• Perceived Pathway

Antibiotic Drug Usein Food Animals
Infection/Colonizationin Humans
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Antibiotic Resistancein Enteric Bacteria
Adverse HealthEvents in Humans
Does antibiotic use in animals affect public
health?
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Antibiotic use in animal agriculture

• Therapeutic
• Metaphylactic
• Prophylactic
• Growth promotion

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Antibiotic use in animal agriculture

• Therapeutic
• Metaphylactic
• Prophylactic
• Growth promotion

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Why metaphylaxis?

• Prevent expected spread of outbreak
• Decreased labor
• Decreased animal stress

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Antibiotic use in animal agriculture

• Therapeutic
• Metaphylactic
• Prophylactic
• Growth promotion

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Antibiotic use in animal agriculture

• Therapeutic
• Metaphylactic
• Prophylactic
• Growth promotion

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What is judicious use?

• Prevention first!Dont get sick!
• Genetics
• Nutrition
• Housing
• Management
• Cleaning and disinfection

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Host
Environment
Pathogen
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What is judicious antibiotic use?

• If sick..
• Get a diagnosis
• Talk with your veterinarian
• Follow label / veterinary instructions
• How much
• How long
• Withdrawal (PQA)

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Judicious Antibiotic Use

• Optimize antibiotic efficacy
• Minimize resistance
• Protect animal health
• Protect the public health