DNA structure and Replication

1
DNA structure and Replication

• Chapter 16

2
Copying DNA

• Any ideas what watson and crick were suggesting
  for how DNA could copy itself?

3
Copying DNA

• Replication of DNA
• Base pairing allows each strand to serve as a
  pattern for a new strand (a template)

4
DNA Replication

• A large team of enzymes coordinate replication

5
Replication Animation

• Video How DNA is replicated
• http//www.johnkyrk.com/DNAreplication.html

6
Enzymes Helicase

• Opens/Unwinds the DNA to allow replication to
  happen

7
DNA polymerase III

• Adds nucleotides only to 3 end
• Nucleoside-p-p-p links to sugar phosphate
  backbone
• Losing 2 phosphates gives energy for bonding

8
Energy from phosphates

• Like ATP
• GTP GDP
• CTP CDP
• TTP TDP