CELL CYCLE

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( 14 June 2006 )
MBI Journal Club on Models of Cell-Fate Regulation
CELL CYCLE
Part Two
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Photograph courtesy of W. C. Earnshaw, Wellcome
Trust Centre for Cell Biology, University of
Edinburgh, Scotland, UK
Interphase
prophase
metaphase
Mitosis
anaphase
telophase
animal cell cycle
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oocyte (definition from biology-online.org) The
developing female gamete before completion and
release. The female germ cells in stages between
the prophase of the first maturation division
and the completion of the second maturation
division.
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MEIOSIS
http//www.bbc.co.uk/schools/gcsebitesize/img/bime
iosis.gif
http//www.accessexcellence.org/RC/VL/GG/images/me
iosis.gif
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embryonic cell cycles
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The Model (heuristic, using a biologists
intuition!)
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YP
M
C2
CP
pM
Y
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High MPF activity
MPF osc.
Low MPF activity
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On the regulation of MPF activity by Cdc25 and
Wee1
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case 1a corresponds to the Cdc25-MPF couple
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Transcritical Bifurcation in Positively Coupled
Cycles
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ss
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mass-action kinetics in graphs shown similar for
Michaelis-Menten kinetics
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Transcritical Bifurcation in Positively Coupled
Cycles
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ss
ss
mass-action kinetics in graphs shown similar for
Michaelis-Menten kinetics
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