Memory: Perceive Store Retrieve

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Memory Perceive Store Retrieve
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Memory Perception
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Memory Storage

• Hippocampus

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Memory Storage

• Hippocampus Basic Anatomy and Pathways

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Encoding and Storage

• Transforming a sensory input into a memory
• The emotional tone of memories
• The time-course of autobiographical memories
• The mystery of storage
• Retrieving old memories

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Storage Long-term Potentiation

• Cortex to Dentate
• Dentate to Ammons Horn (CA3)
• CA3 to CA1

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Storage Long-term Potentiation

• Rapid stimulation of neurons potentiates greater
  responses in the future

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Storage Long-term Potentiation

• Rapid stimulation of neurons strengthens weak
  synapses

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Storage Long-term Potentiation

• Unique responses are produced the rapid powerful
  stimulation

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Storage Long-term Potentiation

• Unique responses are produced the rapid powerful
  stimulation
• These responses may build associations

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Storage Long-term Potentiation

• The Role of the NMDA receptor

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Anterograde Memory Disorder

• Inability to store new information
• Good Immediate Recall
• Good Implicit and Procedural Memories
• Good retrieval of memories that were stored
  before onset of amnesia

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Causes of Memory Disorder

• Surgical resection of the medial temporal lobe
• Wernicke-Korsakoff Syndrome
• Anoxia
• Traumatic Brain Injury
• Brain Tumors
• Dementia-related Illnesses

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Surgical resection of the medial temporal lobe
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Traumatic Brain InjuryAnterograde Retrograde
Amnesia
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Hippocampal Damage Anterograde Amnesia
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Wernicke-Korsakoff Syndrome
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Alzheimers Disease
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Alzheimers Disease
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Memory Assessment

• Verbal Spatial Content
• Immediate vs Delayed Recall
• List Learning
• Prose Learning
• Recall vs Recognition
• The Memory Assessment Scales (MAS)
• Memory Problem Questionaires Rating Scales