Gastroscope

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Gastroscope
Advisor Dr. Ata Akin Design Team Casey
Gavinski Kenneth Hoyt Ashish Patel Kalpesh Trivedi
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Problem Background

• Diabetes Mellitus
• Gastroparesis
• Techniques for Diagnosis
• Invasive
• Non-invasive

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Methods of Diagnosis

• Nuclear Medicine Test
• Patient consumes small amount of radioactive
  material
• Scanner monitors amount of radioactivity in
  stomach
• Upper Gastrointestinal (GI) Endoscopy Test
• Camera inserted into digestive tract
• Visually examines stomach
• Intraluminal Manometry
• Baloon inserted into stomach
• Measures pressure generated by stomach
  contractions
• Electrogastrography (EGG)

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Electrogastrography

• Measurement of Gastric Myoelectrical Potential
  Signals
• Electrodes placed on abdominal surface
• Testing performed during states of Fasting and
  Postprandial
• Correlation between EGG signals
• and gastric motility

Non-Invasive !!
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EGG Signal

• Gastric Myoelectrical Signals (500µV)

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EGG Signal

• Primary Frequency Component
• 3 cpm (0.05 Hz)

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Existing EGG Systems

• Signal Measurement Bandwidth
• 1-18 cpm (0.02-0.3 Hz)
• Primary Frequency
• Stand Alone
• Mobility Limited
• Portable
• No Graphical Display
• Not Stand Alone

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Gastroscope

• Portable
• Stand Alone System
• Graphical Display
• Increased Bandwidth

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EGG Signal

• Secondary Frequency Component
• 50 80 cpm (0.8 1.3 Hz)

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Why the 50 to 80 cpm ?

• 3cpm range requires monitoring throughout fasting
  and postprandial states. (Differential
  Comparisons)
• 50 to 80 cpm range provides consistent results
  with a short time reading.
• 50 to 80 cpm range closely correlated to
  Intraluminal Manometry Test in dogs. (Diagnostic
  Charts Available)
• Create look-up charts for faster more accurate
  diagnosis.

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Gastroscope System Architecture
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Analog Signal Processing

• DC Amplifier
• Instrumentation Amplifier
• Gain gt 10,000
• Low Noise
• Filter
• Low Pass
• Flat Response
• Sharp Roll-off

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Amplifier Schematic
         
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Printed Circuit Board (PCB)
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Amplifier Response
 

• Amplifier and filter response to an input of 100
  µv at 1 Hz

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Amplifier Response (Contd)
 

• Amplifier and filter response to an input of 100
  µv at 15 Hz

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Amplifier Response (Contd)

• Amplifier and filter response to an input of 1 mv
  at 1 Hz

 
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Amplifier Response (Contd)

• Amplifier and filter response to an input of 1 mv
  at 15 Hz

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DSP Flow Chart
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Matlab Simulation
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Matlab Simulation (Contd)
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Alternative System Design

• Laptop Based Design
• Near Real Time Data Analysis
• LabVIEW Software
• Data Storage in Spreadsheet Format
• GUI Interface
• Portable
• Research Applications
• IRB Approved

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Future Work

• Integrated System
• DSP Based Architecture
• Properly Configured ADC
• Touchscreen Display (LCD)

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Senior Design Expenditures
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4 Year Financial Estimation
Note Production at 600 per unit is assumed as
follows Year 1 20 units Year 2 30
units Year 3 40 units Year 4 50 units
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Summary of System Design
Laptop
Freq Mag
Power
START
STOP
RESET
SUMMARY
National Instruments DAQ AI 16E
Amplifier
Fiter
EGG SYSTEM