National Specialist Dermatopathology EQA

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National Specialist Dermatopathology EQA

• Circulation C

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Case 37

• Clinical Female, 49 years old. Sebaceous cyst
  left scapular region

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• Most popular diagnosis..

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• Plexiform schwannoma 48

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Case 38

• Clinical Female, 76 years old. Rapidly growing
  skin lesion on back.
• CD20, CD5 and CD23 positive.
• CD3, CD10 and Cyclin D-1 negative

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• Most popular diagnosis.

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• B cell CLL / SLL 86

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Case 39

• Male, 63 years old.
• Three month history of erosions

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• Most popular diagnosis.

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• Pemphigus vulgaris 88

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Case 40

• Female, 77 years old. One year history of
  chronic skin ulcer. History of bleeding.
  Locally excised.
• ?BCC. ?Lentigo maligna

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• Most popular diagnosis.

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• LMM and BCC 50

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Case 41

• Female, 72 years old.
• Erythematous papules right ankle x 6/12
  ?dermatofibroma ?Bowen's

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• Most popular diagnosis.

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• Molluscum contagiosum 100

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Case 42

• Male, 32 years old.
• Boggy area on occipital scalp

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• Dissecting cellulitis of the scalp 32

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Case 43

• Clinical Female, 86 years. Violaceous eruption
  on abdomen. Patient has myelodysplasia.
• Special Stains diffusely immunoreactive with
  CD43 and focally immunoreactive to CD68 and
  CD117
• negative with antibodies to CD3, CD4, CD8, CD20,
  CD1a and CD30.
• The cells show positivity on histochemistry with
  chloracetate esterase.

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• Most popular diagnosis.

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• Cutaneous myeloid leukaemia 58

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Case 44

• Male, 63 years. Rapidly growing lesion on right
  shoulder. ?Pyogenic granuloma. ?SCC
• IHC shows focal staining for S100, Melan A and
  HMB45

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• Most popular diagnosis.

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• MM (/- sarcomatous/rhabdoid diff.) 99

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Case 45

• Female, 40 years.
• Further excision of infected hidradenoma in
  groin.

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• Most popular diagnosis.

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• Hidradenoma 50
• Atypical hidradenoma 15
• Hidradenocarcinoma 10

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Case 46

• Female, 84 years. Large tumour SCC, amelanoctic
  melanoma or soft tissue sarcoma.
• CD20, CD79a and BCl2 - diffusely positive,
• BCl6, CD10 and mum-1 patchily positive.
• Ki67 positivity in gt80 of the cells.

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• Most popular diagnosis.

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• DLBCL 63

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Case 47

• Male, 52 years.
• Tumour right index finger adherent to skin and
  fascia.
• Cytokeratin 7 positive, CK20 negative, CEA
  negative, S100 focally positive

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• Most popular diagnosis.

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• Digital papillary adenocarcinoma 81

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Case 48

• Male, 62 years.
• Raised pigmented mole on right flank catching on
  belt.

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• Submitted diagnosis.

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• Epithelioid angiomatous nodule

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Case 49

• Female, 69 years. Raised nodule posterior scalp.
  Benign. ?Basal cell papilloma.
• CEA, EMA positive in ductal structures.
• GCDFP15 negative.
• Basement membrane material laminin and COL4
  positive.

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• Most popular diagnosis.

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• Adenoid cystic carcinoma 24

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Case 50

• Male, 36 years. Lump on back for 7 months.
  ?Lipoma. ??Cyst.
• The tumour cells show very strong and diffuse
  CD34 expression.
• They are negative for S100, HMB45, SMA and Desmin.

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• Most popular diagnosis.

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• Dermatofibrosarcoma protruberans 62

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Case 51

• Female, 35 years.
• Pigmented lesion right knee.

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• Most popular diagnosis.

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• Spitz naevus 40

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The End