Faculty Academic Orientation August 14, 2006

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Faculty Academic Orientation August 14, 2006

• Research Opportunities and Resources
• Theodore Kotchen, MD
• Associate Dean for Clinical Research

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Acknowledgement
Joseph Hill, PhD Director MCW Research
Foundation - for generously sharing a portion
of his slide-set for this talk.
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Goals

• Outline the MCW Research Infrastructure
• Identify Opportunities for Research Education
• Describe strategies for research program
  development/funding

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1. Infrastructural components of a strong
research environment
Adequate research space - bench space (proximity
to office, collaborators, core facilities) -
dry lab space - computational support,
internet and journal access
Support for research administration -
secretarial support (varies by department) -
guidance through the grant preparation process,
IRB application, consent forms, IACUC
requirements, biosafety issues,
radioactive materials use (Research office). -
retrieving and collating institutional
information and statistics (e.g. for
training grants, program project grants) - legal
support for inter-institutional MOUs, technology
transfer, contracts and grants with industry
partners (MCW Office of General
Counsel, Grants and Contracts Office).
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Infrastructural components of a strong research
environment(part II)
Core facilities - basic sciences (sophisticated
microscopy, molecular biology,
protein/nucleotide identification and synthesis,
cell-sorting, histology, etc.) -
IT/informatics (database creation and
maintenance, distribution, security) -
biostatistical consultation - access to patients
and patient information - collaborative hospital
environment - varied clinical demographic
structure (e.g. Childrens hospital, VA
Hospital, private hospitals, outpatient clinic
facilities)
Diverse clinical and research faculty
Training programs - to develop junior faculty,
students, fellows, post-docs
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MCW Research Office Infrastructure
BRC (Biomedical Resource Center) aka Animal
Care Center Dr. Robert Faith Human Research
Protection Unit Dr. David Clark,
Assistant Dean for Clinical Research IRB
(Institutional Review Board) DSMB (Data Safety
Monitoring Board) Library and Information
Programs Mary Blackwelder IT/informatics
(database creation and maintenance,
distribution) - eIRB - Angel (Software
Application) - Reference management systems,
reference database, research material resources,
PDA downloads
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MCW Research Office Infrastructure(part II)
Grants and Contracts April Haverty,
LD Pre-grant and contract administration. Safety
Office Kurt Kleparski Biosafety committee
(e.g. use of infectious organisms, personal
protective equipment, hazardous material,
chemical hygiene, safety plans, material safety
data sheets) IBC Drs. Phillip Pratt and
Thomas Zahrt Use of recombinant DNA and
Pathogens Radiation Safety Office Mark
Martz
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Breadth of MCW Research Support

• New Investigator Awards (RAC, 12,500)
• New Idea Awards (RAC 12,500)
• New, Intermediate and Senior Researcher Awards
  (Healthier Wisconsin (150,000), RAC, GCRC awards
  (40,000)
• Interdisciplinary Center-Based Awards (e.g. DDC,
  Cancer Center, GCRC Translational research)
• Bridge Support (RAC, 15,000)
• SPUR (Summer Program for Undergraduate Research)
• Medical Student Summer Research Program
• Minority Summer Research Training

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2. Research Educational Opportunities

• Clinical Research Scholars Program
• GCRC (statistical inference and design, research
  data management, pharmacogenomics, bioethics,
  grant writing, preparing oral and poster
  presentations, etc.)
• IRB (Research Community Forum, on-line help with
  completing IRB forms, consent forms, completing
  mandatory clinical research training, on-line
  training for eliciting informed consent.)
• Radiation Safety - classes and training
• Library Services Medline and other database
  searches.

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Communication and Research Implementation
3. Strategies for Research Development

• Identify Collaborators
• Obtain Information on Extramural Funding
• Identify Core Facilities/Centers
• Initiate Consulting/Industry Collaborations
  (Research Foundation)

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Identifying Potential Collaborators

• Department Web Pages
• Contact MCW Centers and Institutes
• Medline Search for Publications
• NIH Grants Database

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MCW Departmental Web Sites

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MCW Departmental Web Sites

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MCW Departmental Web Sites
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MCW Departmental Web Sites

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MCW Special Programs/Centers (30)

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Core Facilities/Resources

• Free-Radical Core Facility
• Transgenic Core
• Cellular Imaging Core
• Flow Cytometry Core
• Cancer Molecular Core Facility
• Protein/Nucleic Acid Core Facility
• Etc.

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CRISP Search for NIH Grants
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CRISP Search for NIH Grants
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Extramural Funding Opportunities

• Federal (NIH)
• Non-Profit (AHA, Foundations)
• Industrial (e.g. Pharma, Medical Device
  Companies, Start-ups)

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NIH Funding Opportunities
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NIH Guide to Grants and Contracts-Getting the
information
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NIH Program Announcement
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Sponsored Programs Information Network (SPIN)
All Sponsors
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MCW Research FoundationJoseph Hill, Ph.D.
Director

• MCWs Interface with industry
• Identify investors
• Commercialize Discoveries ? Translational
  Research ? Products
• Receives reports of new discoveries
• Protect Discover (Patents)
• License new technologies to pharmaceutical and
  medical device companies
• Start new Companies
• Generate income for investigator, department, MCW

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Questions Contact Info
Office of Research David D. Gutterman
MDNorthwestern Mutual Professor of
CardiologySenior Associate Dean for
Research414/456-8495 Diane L.
GromowskiDepartment Administrator414/456-8345 L
ynne M. ProstAdministrative Coordinator
II 414/456-8508