BIOINFORMATICS DEVELOPMENTS IN INDIA

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BIOINFORMATICS DEVELOPMENTS IN INDIA

• Dr. T. Madhan Mohan
• Madhan.dbt_at_nic.in
• Director
• Department of Biotechnology
• New Delhi
• httpwww.btisnet.gov.in/www.dbtindia.gov.in

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DBT
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Bioinformatics in India

• Department of Biotechnology created in 1986
• Bioinformatics programme started ever since
• Biotechnology Information System Network
  (BTISnet) in 1987
• BTISnet today has 65 institutions and
  universities
• Emphasis on infrastructure creation and human
  resource development
• Biotechnology in India has greatly benefited from
  the capacity building in Bioinformatics
• Dedicated virtual private network connecting the
  major centres sharing of data as well as
  computing resources

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Major Achievements BTIS

• First Distributed Science Network
• Sensitization of life scientists for use of
  computers
• Driven the better infrastructure for networking
  and visualization
• Improvement of Quality of research in modern
  Biology/Life Sciences

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Bioinformatics Facilities in India
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BIOGRID INDIA
Internet
MK Univ., Madurai
IGIB, Delhi
South Campus, DU, Delhi
Service Providers VPN Network
IMT, Chandigarh
Deptt. Of Biotecdhnology, Delhi
Univ. of Pune
IIT, , Delhi
CDFD, Hyderabad
Router
NBRC, Gurgaon
NII, Delhi
IISc, Bangalore
JNU, Delhi
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MIRROR SITES

• EMBnet (CDFD)
• PDB (IISc University of Pune)
• GDB (IISc.)
• EBI Databases (Pune)
• Plant Genome Databases (JNU)
• Public domain Biotech Software (IMTECH)

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Educational Activities of India in Bioinformatics
Two forms of initiatives are in operational

• Short-Term Training
• Nationwide trainings
• and workshops
• Presently around 100
• organised per year in
• seven defined areas
• More than 10000 trained
• so far

• Long-Term Training
• Advanced Diploma Courses
• in five universities
• M.Sc., M.Tech., Ph.D. courses
• in Bioinformatics

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Job opportunities in Bioinformatics
Qualification Experience
Job Title

• Post graduates and ,Doctorates
• Bachelor degrees / 3 year diploma holders
• 3) Degree with one year course in computers

Formal Training and understanding market
requirement of Bioinformatics Sound knowledge
in Molecular Biology and programming Good
typing speed, Knowledge in molecular Biology and
computer application
Group leaders / Sr. Executives / Scientists/
Faculties System Analyst Technical Asst./
Programmer / COs / DEOs
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INTEGRATION OF BIOTECHNOLOGY DATABASES ON BTISNET
BioGrid Nodes/ Server High Speed Network
Medical Biotechnology
Agricultural Biotechnology
Medicinal or Aromatic Plants
Animal Biotechnology
USERS
BIOTECHNOLOGY PORTAL
Aquaculture Marine Biotechnology
Biodiversity Databases
Mirror Sites on Major Databases
Molecular Biology
BTISNet Software package
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In-house software development

• GeneScan, GenEvolve, PROCOR
• PLHOST
• APSSP (Protein structure prediction), MHCBN
• PCR s/w for setting PCR reactions
• LOOPSEARCH, CONFPLOT
• VirGen, CE, AVIS
• Micro array analysis (Avadis), Genome annotation
  (Acuris), Oligonucleotide probe design (Sarani)
• BioSuite

• JNU, Delhi
• IGIB, Delhi
• IMTECH, Chandigarh
• Devi Ahilya University
• Bose Institute, Kolkatta
• University of Pune, Pune
• Strand Genomics, Bangalore
• TCS, Hyderabad

These efforts needs to be strengthened with Human
resource development
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Integration of Bioinformatics Biotechnology

• Collaborative effort
• RFP (Request for Proposals) in following areas
• Parasitic diseases
• Agro-biotech
• Herbal medicine
• Clinical Data management

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Major Research Areas in Bioinformatics
2
15
20
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Mech. Of Diseases
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30
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Total number of Research Publications in last two
years is 392
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Phenotype
Genetical Genomics
Statistical Genomics
Computational Genomics
Functional Genomics
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Functional Genomics ?
Genome sequence
mRNA Transcriptomics
Protein Proteomics
Metabolites Metabolomics
Phenotype
Reverse Genetics
Forward Genetics
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Need of Tie ups between Wet In-Silico Labs
Wet Lab Experiments(High throughput technologies)
In-Silico technologies (Bioinformatics)
Knowledge Discoveries Products
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Strategic alliance Partnerships
IT Industries
Hospitals for Clinical records
Software Expertise
Pharma Companies
Academic RD Institution
BIOINFORAMTICS
Health Care System
Hardware Supplies
Biotech Companies
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Bioinformatics Market
Global Bio-Informatics Market 1.2bn In
2004 Overall Market Size Projected to reach USD
1.7 bn by 2006 Indian Bioinformatics Market has
touched USD22 Million in 2004 Indian
Bioinformatics is growing at the rate of 40 per
annum (Source CII)
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Areas of opportunity in India

• Bioinformatics
• Vaccines, dignostics and therapeutics
• Biomedical devices, instruments and sensors
• Bioartificial organs using tissue engineering and
  stem cells
• Clinical trial and contract research
• Agriculuture disease and pest resistant,
  drought and salinity tolerant seeds and plants
• Biofertilisers and Biopesticides

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Advantages for India
Strong IT capabilities R D strength in Modern
biology Highly trained manpower in biotechnology
and Bioinformatics Rich Biodiversity Diverse
ethnic population Strong Biotechnology
Infrastructure Wide Networking of Institutions
and Scientists. Industrial enterprise.
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Invitation to InCoB2006-http//www.incob2006.in
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International Conference on Bioinformatics (InCoB)

• InCoB is the annual international conference of
  the Asia Pacific Bioinformatics Network
  (APBioNet). The main objective of the InCoB is to
  provide a platform for experts and budding
  bioinformaticians to discuss and exchange ideas
  and cards on the development of Bioinformatics in
  the Asia Pacific region.

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Asia Pacific Bioinformatics Network (APBionNet)

• The Asia Pacific Bioinformatics Network
  (APBioNet) is a non-profit, non-governmental,
  international organization. It focuses on the
  promotion of bioinformatics in the Asia Pacific
  Region. Since 1998, its mission has been to
  pioneer the growth and development of
  bioinformatics awareness, training, education,
  infrastructure, resources and research amongst
  member countries and economies. Its work includes
  the technical coordination and liaison with other
  international bodies such as the EMBnet.

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Date and Venue (Tentative)

• Date Decembers 18th 20th, 2006
• 2. Venue Ashoka Hotel, New Delhi

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Organizing Institutes
Indian Institute of Technology
www.iitd.ernet.in
www.scfbio-iitd.res.in
Jawaharlal Nehru University
www.jnu.ac.in
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Concluding Remarks

• India is well placed to take up global
  leadership in genome analysis as is in a unique
  position in terms of genetic resources has
  several ethnic population that are valuable in
  providing information about diseases
  predisposition and susceptibility, which in turn
  will help in drug discovery.
• Welcome to InCoB2006 18-20th December 2006, New
  Delhi, India, Pl. visit www.incob2006.in
• Thank you.