IT Innovation in India

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IT Innovation in India
Ocimum Biosolutions enabling RDTM www.ocimumbi
o.com

• December 5th 2005

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Whats in a name?

• That which we call a rose by any other name
  would smell as sweet
• Ocimum
• Indian Name Tulsi
• Botanical Name Ocimum Sanctum
• Common name Holy Basil

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Key Members of Mgmt.

• Ms. Anuradha Acharya, Founder CEO
• Ms.Acharya has an MS in Management Information
  systems from the University of Illinois at
  Chicago. She also has an MS in Physics from same
  school. She has a Bachelors and Masters from the
  Indian Institute of Technology at Kharagpur. She
  worked as an IT professional for six years prior
  to founding Ocimum.
• Dr. P. Sujata, PhD, Founder CSO
• Dr. Sujata has done post-doctoral work in
  Université de Perpignan, France, and has over 15
  years of experience in Molecular Biology and
  Biotechnology. She has also worked on DNA
  sequencing and Genome mapping at Texas AM
  University, USA, and has Biotechnology and
  Functional Bioinformatics experience at one of
  the largest life sciences companies in the US.
• Mr. Subash Lingareddy, Founder CFOMr.
  Lingareddy is a Financial Professional and a CFA
  charter holder with over six years of experience
  working in several roles from an equity analyst
  to a financial risk manager prior to joining
  Ocimum. He has an MBA from the University of
  Illinois at Urbana Champaign with a concentration
  in Corporate Finance. He has a MS in Financial
  Mathematics from the University of Chicago
  specializing in risk management. He has a
  Bachelors in Physics from the Indian Institute of
  Technology at Kharagpur.

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What integrates our approach
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Quality certifications

• ISO 90012000
• Process Innovation
• Datatracker Evolved our own ERP for capturing
  quality processes, employee management, project
  management, as an internal CRM, Business
  Development etc

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Accolades

• Deloittes Technology Fast 50 India ranked 4th
  all India
• Deloittes Fast 500 Asia Pacific

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Our Customers- Partial List
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Why Us- What differentiates us

• Culture of innovation in the organization
  TRADITION, Openness, creativity, ESOPS
• Multiple products of world class standards
• More than a 100 international customers
• Committed management and employees

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Introducing OptGeneTM

• OptGene is a multi-platform compatible
  bioinformatics product that enables design of
  genes with optimized features for expression in
  organism of choice. The software exploits
  redundancy in codon usage to engineer desired
  features into the targeted gene. Functional
  Features of OptGene include
• Back translation by matching codon usage
  frequency in host organism without modifying
  amino acid sequence
• Searching for sequence patterns or signals (mRNA
  destabilizing signals, hairpin loops, tandem
  repeat codons, GC content, etc.)
• Scanning for hairpin loops
• Restriction site analysis without altering amino
  acid sequence
• Intuitive six frame ORF analysis

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Optgene-The preferred solution

• How Scientists optimized genes before OptGene
• Excel or a combination of different programs
• What was the issue
• Small calculations can lead to big losses
• Time consuming
• Cannot get all possible answers to your solution
  immediately
• Ocimum IT solution to the problem
• Helps them optimize genes using a software
  solution faster.
• Further innovations and future potential
• Automation

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Building blocks of OptGene

• Adaptation of the codon usage to that of host
  organism
• Removal of RNA destabilizing signals and other
  undesirable patterns.
• Total elimination or destabilization of RNA
  Secondary Structures
• Reducing transcription regions in unused reading
  frames
• Insertion/ deletion of restriction sites

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OptGene becomes more appealing

• Single click to codon optimization
• Unique sequence visualization to track
  modifications form step-to-step of optimization
  process
• Easy management of Restriction Enzymes list,
  Patterns list and direct download of Codon usage
  tables
• High flexibility in the optimization work flow

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Plan to innovate further

• Automation
• Automating the entire gene optimization process
  to enhance expression level
• Rare codons
• Eliminating rarely used or not utilized codons
  (rare codon) in the optimized sequence
• Scoring scheme
• Calculation of the average fitness score of the
  optimize sequence based on the codon adaptation
  index for validation
• Comprehensive report generation
• Displaying codon quality distribution as well GC
  content graphically in final report

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Ocimum Culture

• What is special about our team ?

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Marketing Plan

• Word of mouth works best if you have a great
  product in a niche segment.
• Advertisements both on the web and magazine
• Active Sales Team in dense markets like the US,
  India and Europe
• Distributors in other regions

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Sales Distribution Channels
UBI
World Fusion
Science Partners
SciMax
Eisenberg Brothers
Office
Digigenomics
Sales Team
Sales Team
Office
XICG
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Revenue Models

• OptGene is a niche product and is the first and
  only commercial product of its kind
• Pure Software sale- Companies or labs that do
  gene optimization or those that provide a wet lab
  component
• Software and Service agreement
• For small labs that have minimal requirement for
  optimization
• For large labs that constantly require
  optimization