ANA B' CHEPELINSKY, Ph'D'

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National Institutes of Health International
Programs Latin America and the Caribbean

• ANA B. CHEPELINSKY, Ph.D.
• Program Director for the Americas
• Division of International Relations
• Fogarty International Center
• National Institutes of Health

e-mail abc_at_helix.nih.gov
http//www.fic.nih.gov
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National Institutes of Health
Fogarty International Center
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National Institutes of Health

• Mission
• NIH conducts and supports basic, applied,
• clinical and health services research to
• understand the processes underlying
• human health and to acquire new
• knowledge to help prevent, diagnose, and
• treat human diseases and disabilities.

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NIH fulfills its mission by

• Conducting research in its own laboratories.
• Supporting the research of non-Federal scientists
  in universities, medical schools, hospitals, and
  research institutions throughout the United
  States and abroad
• Helping in the training of research investigators
  in the United States and abroad
• Fostering communication of medical and health
  sciences information in the United States and
  abroad

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FY 2004 Budget 28.04 Billion
Training 3 749 million
Research Project Grants 55 15 billion
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NIH supports international programs through a
range of mechanisms

• Grants
• Contracts
• Foreign Components to US awards
• Visiting Program
• Fogarty programs

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NIH Cross-Cutting Initiative NIH Roadmap

• Accelerate basic research discoveries and speed
  translation of those discoveries into clinical
  practice
• Explicitly address roadblocks that slow the pace
  of medical research in improving the health of
  the American people

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Research Teams of the Future

• Explore new organizational models for scientific
  teams
• Multidisciplinary and interdisciplinary
• Larger, coordinated resource sharing
• Preserve the investigator(s)-initiated strategy

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The NIH Roadmap for Medical Research 3 Themes
New Pathways to Discovery
NIH
Reengineering the Clinical Research Enterprise
Research Teams of the Future
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Misión del Fogarty International Center, NIH

• Promover y apoyar la investigación y el
  entrenamiento científico para disminuir las
  desigualdades en salud global

Science for Global Health
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FIC fulfills its mission by

• Supporting training to strengthen international
  research capacity
• Promoting strategic alliances
• Creating collaborative international research
  networks to improve global health

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Fiscal Year 2003NIH Research Awards by Region
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NIH collaborative activity FY 2003
in Brazil, Argentina and Mexico
Foreign Visiting
Direct Component Program Award
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Fogarty International Center
Research and Training Opportunities in Global
Health

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Characteristics of FIC Programs

• Target low- and middle-income countries
• Collaborative (usually US-foreign)
• Multidisciplinary
• Addresses a perceived international need (based
  on targeted studies, e.g. WHO and IOM
  consultations)

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Fogarty International Center Programs

• International research grant programs
• R series grants
• R(01) RESEARCH
• R(03) - small research
• International training grant programs
• D43 training programs
• International fellowships and other opportunities

Fogarty International Center
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From Brain Drain to Brain Gain The FIC-NIH
Global Health Research Initiative Program for New
Foreign Investigators GRIP
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FIC-NIH Global Health Research Initiative
Program For New Foreign Investigators (GRIP)

• Promueve la reinserción de investigadores al
  regresar a sus paises de origen al finalizar su
  entrenamiento postdoctoral en NIH.
• Disminuye la fuga de cerebros y asegura el
  retorno de investigadores a sus paises de origen
  para que los paises en desarrollo no pierdan a
  sus científicos.
• El programa GRIP es parte del esfuerzo de FIC/NIH
  para promover la capacidad e infraestructura
  científica en los paises en desarrollo.

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GRIP Purpose

• Help overcome major barriers to returning
  scientists to developing countries
• Increase the pool of foreign researchers
• Work on problems of local concern
• Strengthen the research infrastructure in
  developing countries

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Individual Eligibility for GRIP

• Trained in the intramural program at NIH or under
  Fogarty D43 training grants
• Two years of training or one year of training and
  one year of mentored research
• From developing countries
• Returning to developing countries
• Soon to complete or recently completed (within 3
  years) or training
• Work done relating to scientific needs of the
  country or region

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GRIP Support

• Up to maximum 50,000 per year total for maximum
  5 years
• Applicant must devote at least 50 effort to
  project
• Grant will support up to 50 salary
• Funds may be used for research equipment,
  supplies, travel or other research personnel's
  salary working on the same project.

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Collaborations

• Encourage collaborations with training
  institution
• Formal collaboration is not necessary
• Ongoing mentorship and partnership

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GRIP PROGRAM STARTED IN 2002

• 2002 19 awards
• 2004 15 awards
• 2005 13 awards
• Currently 47 GRIP grantees

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47 Current GRIP Grantees

• 18 in Latin America
• Mexico (6)
• Brazil (4)
• Argentina (3)
• Chile (2)
• Uruguay (2)
• Colombia (1)
• 17 in Africa
• Kenya (2), South Africa (3), Uganda (2), Tanzania
  (1), Malawi (1)
• 14 in Asia
• China (4), Hong Kong ((2), India (5), Thailand
  (3)
• 6 in Eastern Europe
• Bulgaria (1), Czech Republic (2), Estonia (1),
  Poland (1), Hungary (1)

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NIH Visiting Program Latin American Fellows 5
NIH Visiting Fellows
NIH GRIP Program Latin American GRIP Grantees
38 total GRIP awarded
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R01 GRIP Grants
The number of GRIP awards will depend upon the
quality of the applications received. This
Global Research Initiative Program (GRIP)
provides the opportunity for junior foreign
scientists to compete for funds through a
peer-reviewed process. The GRIP Program allows
the continuation of promising independent
research careers that will be of benefit to the
investigators' home countries and the world at
large.
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Fogarty International Research Collaboration
Award FIRCA (R03)

• Fosters international research partnerships
  between NIH-supported U.S. scientists and
  collaborators in developing countries in areas of
  mutual interest
• Provides a stipend for the foreign investigator,
  direct costs for equipment and supplies for the
  foreign laboratory and travel funds

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FIRCA Biomedical/Behavioral and Social Sciences

• 32,000/year direct costs to foster research
  partnerships between U.S. scientists and their
  collaborators in countries of the developing
  world. Three years. Renewable.
• U.S. scientists who have an eligible NIH research
  grant may apply. 
• All areas of biomedical and behavioral research
  supported by NIH are eligible.

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HIV/AIDS and Related Illnesses Collaboration
Award (FIRCA-AIDS)

• To foster international research partnerships
  between NIH-supported U.S. scientists and their
  collaborators throughout the world in all aspects
  of HIV-AIDS research and new and resurgent
  infectious diseases related to HIV infection
• The AIDS-FIRCA program aims to enhance the U.S.
  investigator's research grant while benefiting
  the scientific interests of the foreign scientist

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International Training and Research Program in
Emerging Infectious Disease

• Purpose
• To foster collaborative research with regions of
  the world where new or reemerging infections are
  most likely to occur due to population patterns
  and ecological disturbances.
• Objectives
• Train laboratory scientists and public health
  workers in developing countries and the U.S. in
  emerging and re-emerging infectious diseases
  research, control and prevention strategies and
  their implementation and evaluation.
• Facilitate international collaboration on
  emerging infectious diseases research, including
  the conduct of research in developing countries.

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Global infectious Disease Research Training
Program Institutional Grant

• Non-HIV/AIDS infectious disease research
  (laboratory, clinical, epidemiological or social
  science) training.
• Focus on infectious diseases relevant to
  developing endemic countries.
• Building critical mass researchers leading to
  scientific research capacity and sustainability
  at a developing country institution.

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Brain Disorders in the Developing World Research
Across the Lifespan

• For collaborative research between high-income
  and low to middle-income country scientists
  Either partner may be the Principal Investigator
• Focus on nervous system function and disorders
  relevant to developing countries.
• Training component must also be included
• 29 Planning grants awarded.
• R21 Planning grants- open competition
• R01 open only to previous R21 grantees .
• CONTACT Dr. Kathleen Michels, michelsk_at_NIH.GOV
  www.fic.nih.gov

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Training Programs that include Brain Disorders

• Genetics (psychiatric genetics, genetic
  epidemiology, neurodegenerative diseases,
  genetics of drug dependence)
• Global Infectious Diseases
• Environmental and Occupational Health
• International Clinical, Operational, and Health
  Services Research Training

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International Clinical, Operational, and Health
Services Research and Training (ICOHRTA-1)

• First series of grants focused mostly on mental
  health and drug abuse -related research training
  for clinical, health services and operational
  research
• 14 Programs for collaborative research training
  between U.S. Institutions and institutions in
• Brazil, China, Czech Republic, India, Peru,
  Poland, South Africa, Turkey, Ukraine, Vietnam
• See www.fic.nih.gov and go to ICOHRTA page for
  list of programs and contacts
• Contact Kathleen Michels, 301-496-1653,
  michelsk_at_nih.gov

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International Collaborative Trauma and Injury
Research Training Program (ICTIRT)

• To develop innovative research training programs,
  between developed and developing country
  institutions, to build a critical mass of
  scientists, health professionals and academics
  with human trauma and injury expertise within the
  developing country.
• Program Officer Dr. Aron Primack.
  PrimackA_at_mail.nih.gov
• http//grants1.nih.gov/grants/guide/pa-files/PAR-
  04-083.html

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International Training and Research Program in
Environmental and Occupational Health

• Expands U.S.-foreign collaborative training and
  research in environmental and occupational
  health.
• Enables U.S. institutions to support
  international training and research programs in
  environmental and occupational health for
  scientists from developing nations.

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Informatics Training for Global Health

• Five year awards for training programs to enhance
  global health informatics capacity in low- and
  middle-income countries in collaboration with US
  institutions.
• Foreign institution must be participant in 3
  active NIH-supported grants at time of award
• Training must be integrated with research
  programs at the foreign site.
• Anticipate next RFA in 2008

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Framework Programs for Global Health
Purpose To catalyze and support the efforts of
universities in the US and in low- and
middle-income countries to develop integrated,
multidisciplinary programs in Global Health

• Eligibility
• Single institutions in US or developing countries
  with at least 5 active NIH grants in global
  health research or training (1 D43)
• Multiple institutions may be partners for the
  purposes of developing joint curricula,
  activities, or degree programs.

http//www.fic.nih.gov/programs/framework.html Con
tact Flora Katz, Ph.D. Email
katzf_at_mail.nih.gov
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FIC/NIH Latin America and the Caribbean
Cooperation
International Maternal and Child Health Research
and Training Program (MCH) Argentina, Brazil,
Chile, Dominican Republic, Guatemala, Mexico,
Panama, Peru, Uruguay. Brain Disorders in the
Developing World Research Across the Lifespan
Argentina, Brazil, Colombia, Mexico, Peru,
Venezuela. International Bioethics Education and
Career Development Award programs by grantees in
Argentina and Chile involve trainees in
Argentina, Mexico, Chile, Brazil, Dominican
Republic, Colombia, Peru. International Tobacco
and Health Research and Capacity Building
Program Argentina, Brazil, Dominican Republic,
Mexico. Stigma and Global Health Research
Program Argentina, Brazil, Haiti.
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FIC/NIH Latin America and the Caribbean
Cooperation
AIDS International Training and Research Program
(AITRP) Brazil, Haiti, Peru, Dominican Republic,
Colombia, Guyana, Jamaica, Haiti, Nicaragua,
Mexico, Argentina, Chile, Trinidad/ Tobago,
Bahamas, Barbados. Global Infectious Disease
Research Training Program (GID) Brazil,
Colombia, Peru, International Malaria Research
Training Program (IMRTP) Colombia. International
Clinical, Operational, and Health Services
Research and Training Award (ICOHRTA-1) Brazil,
Peru. International Clinical, Operational, and
Health Services Research and Training Award
ICOHRTA AIDS/TB Brazil, Mexico, Haiti, Peru.
Ecology of Infectious Diseases Initiative
Belize, Peru.
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FIC/NIH Latin America and the Caribbean
Cooperation
International Training and Research Program in
Environmental and Occupational Health (ITREOH)
grantee programs in Brazil, Chile, Colombia,
Costa Rica, Mexico, Nicaragua, Peru, Uruguay,
Venezuela. International Training and Research
Program in Population and Health Argentina,
Bolivia, Brazil, Chile, Costa Rica, Dominican
Republic, Ecuador, El Salvador, Mexico,
Nicaragua, Paraguay, Peru. Health, Environment,
and Economic Development (HEED) Program Mexico,
Brazil, Ecuador. International Collaborative
Genetics Research Training Program involves Costa
Rica, Venezuela. International Cooperative
Biodiversity Group (ICBG) Costa Rica, Jamaica,
Panama Informatics Training for Global Health
(ITGH) Brazil, Peru.
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Science For Global Health
www.nih.gov
www.fic.nih.gov