NEW HEMOSTATIC AGENTS

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NEW HEMOSTATIC AGENTS

• Combat GauzeTM
• WoundStatTM

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Scientific Study

• Laboratory studies have demonstrated two new
  hemostatic agents are superior to the current
  hemostatic agents
• New Hemostatic Agents
• Combat Gauze (CG)
• WoundStat Granules (WS)
• Current Hemostatic Agents
• HemCon Bandage (HC)
• Trauma Stat bandage (TS)
• Celox Powder (CX)
• Plain gauze (PG)

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Summary Results Total Blood Loss
P0.007 (ANOVA)
CG vs. CX vs. WS NS
Plt0.05 vs. HC

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Summary ResultsTotal Hemostasis Time
P 0.002 (non parametric ANOVA)
Plt0.01 vs. HC
CG vs. CX vs. WS NS


Plt0.05 vs. HC

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Summary Results Survival Time
Plt0.05 vs. HC
WS (100)
CG (80)
CX (60)
Plt0.0001 (Logrank test)
PG (33)
TS (20)
HC (10)
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Results

• Both agents (Combat GauzeTM and WoundStatTM)
  demonstrated an increased ability to stop
  bleeding over all other hemostatic agents.
• Both agents are pro-coagulant and actually cause
  the blood to clot.
• Neither agent has any exothermic (heat
  generating) reaction.
• Cost of both is significantly less than HemConTM

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Application Procedure

• All hemostatics work better when the hemorrhage
  has been controlled by pressure to a pressure
  point proximal to the wound.
• This slows or stops the blood to the wound,
  allowing better visualization and better
  application of the hemostatic agent

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What is QuikClot Combat Gauze

• Combat Gauze is a 3-inch x 4-yard roll of
  sterile Hemostatic Gauze.
• Combat Gauze is impregnated with kaolin which
  is an advanced hemostatic agent.
• It controls moderate to severe blood loss by
  rapidly promoting coagulation.

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Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
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How does it work?

• Combat Gauze causes rapid, localized
  coagulation.
• It forms a stable blood clot in a variety of
  combat wounds.
• It does not absorb into the body and is safe to
  leave in the wound until further medical care is
  available.
• Combat Gauze does not produce any heat.
• Combat Gauze controls bleeding faster than
  conventional methods.

9
Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
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Expose Wound Identify Bleeding

• Open clothing around wound.
• If possible, remove excess pooled blood from
  the wound while preserving any clots already
  formed in the wound.
• Locate source of most active bleeding.

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Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
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Pack Wound Completely

• Pack Combat Gauze tightly into wound and
  directly onto bleeding source.
• More than one gauze may be required to stem
  blood flow.
• Combat Gauze maybe re-packed or adjusted into
  the wound to ensure proper placement

11
Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
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Apply Direct Pressure

• Quickly apply pressure until bleeding stops.
• Suggested time is 2 to 3 minutes of continuous
  contact.
• Reassess for proper and effective placement.
• Combat Gauze may be repacked if initial use
  fails to provide hemostasis.

12
Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
13
Bandage over Combat Gauze

• Leave Combat Gauze in place.
• Wrap to effectively secure the dressing in the
  wound.

Although the ETB is shown in this picture, the
wound may be secured with any compression
bandage, Ace wrap, roller gauze, or cravat.
13
Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
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Transport Monitor Casualty

• Do not remove the bandage or Combat Gauze.
• Transport to next level of medical care as soon
  as possible.

14
Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
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Document on Casualty Card

• Document CG on the casualty card, or attach
  the empty package with the casualty.
• This will identify the major hemorrhage to the
  field surgical team.

15
Combat Medical Systems, LLC, Tel [phone],
Fax [phone], Website www.combatgauze.com
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Combat Gauze Video6510-01-562-3325
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WoundStatTM6510-01-563-6628
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WoundStatTM

• WoundStatTM is a 5.5 ounce package of
  non-metallic clay mineral (smectite) composed of
  hydrated sodium, calcium, aluminum silicate.
• This product swells when exposed to water or
  blood and forms a clay-like material with high
  plasticity and tissue adhesiveness.

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WoundStatTM DirectionsTear Open Pouch
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WoundStatTM DirectionsPour Contents into Wound
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WoundStatTM DirectionsFirmly pack WoundStatTM
into all areas of the wound
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WoundStatTM DirectionsPress and hold pressure
for three minutes
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WoundStatTM DirectionsIf re-bleeding occurs,
remold and repack original product DO NOT REMOVE
THE ORIGINAL PRODUCT!
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WoundStatTM DirectionsBandage and secure wound
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WoundStatTM DirectionsMove patient as quickly as
possible
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WoundStatTM Video
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If Combat GauzeTM does not control the bleeding

• Medics should remove the Combat GauzeTM and apply
  WoundStatTM as directed on the WoundStatTM
  package.
• An additional three minutes of pressure needs to
  be applied to the wound after the WoundStatTM has
  been applied and packed into the wound.

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Conclusion

• Two new hemostatic agents are available for use.
• Both are superior in laboratory models in
  stopping bleeding than the current hemostatic
  agents.
• Both are easy to use
• Both actually promote blood clotting
• Both are cheaper than HemConTM Bandages

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QUESTIONS?