Tony G'Waldrop

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UNC-Chapel Hill and theNIH Roadmap
NIH ROADMAP
Tony G.Waldrop Vice Chancellor Research and
Economic Development
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NIHsRoadmap Vision

• Est. 2 of total NIH budget
• Primary funding source tax on NIH institutes
• Emphasis
• Attacking difficult problems
• Interdisciplinary collaboration
• Translation to clinic
• Computation/informatics
• Allied projects will make Roadmap much larger
  than its core funding

Dr. Elias Zerhouni
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Themes

• New Pathways to Discovery
• Building Blocks, Pathways, and Networks
• Molecular Libraries and Imaging
• Structural Biology
• Bioinformatics and Computational Biology
• Nanomedicine
• Research Teams of the Future
• High-Risk Research
• Interdisciplinary Research
• Public Private Partnerships
• Re-engineering the Clinical Research Enterprise
• Clinical Research

Dorsal root ganglia neurons (Annette Markus)
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RoadmapPlanningat UNC

• September, 2003 Dr. Zerhouni announces the
  Roadmap
• January, 2004 12-member Carolina Roadmap Task
  Force is convened
• March, 2004 Task Force report recommends
• Create a campus-wide organization for Roadmap
  projects
• Demonstrate administrative support
• Appoint a Roadmap chair
• Provide staff and resources

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UNCsResponse

• NIH Roadmap Executive Committee
• Chair Rudy Juliano, Professor of Pharmacology
• Executive Committee members
• Kim Brouwer, Chair Pharmacotherapy, Pharmacy
• Barbara Entwisle, Director, Carolina Population
  Center and Professor of Sociology
• Michael Fried, Professor of Medicine and
  Director, Hepatology Division of Gastroenterology
  and Hepatology
• Daniel Reed, Vice Chancellor for Information
  Technology and Director, Institute for
  Renaissance Computing
• Rich Superfine, Professor of Physics
• David Savitz, Chair of Epidemiology

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CampusSupport

• Roadmap Committee will steer efforts to
• Build research teams and partnerships at UNC
• Liaise with NIH on Roadmap
• Highlight interdisciplinary research
  (workshops)
• Facilitate development of proposals
• A new staff position (Karen Stone)
• Seed funding from VC for proposal development
• Additional support from
• Offices within Research and Economic Development
• College of Arts and Sciences
• Schools of Medicine, Dentistry, Public Health

Freeze-dried, rehydrated platelets in a canine
carotid artery. (Tom Fishcher)
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Action

• The first round of Roadmap P20 RFAs yields
  multiple UNC proposals
• REC meets with multiple Departments/Centers
• VCs Workshops In Interdisciplinary
• Research
• Emerging Initiatives
• Metabolomics Steve Zeisel, others
• Stem Cells TransplantationJon Serody, others
• Peridontal DiseaseSteve Offenbacher, others
• Biomedical Research Imaging CenterEtta Pisano,
  others
• Pathways NetworksKlaus Hahn others
• Child abuse physiological changes- Jonathan
  Kotch, others
• Other projects??

Fluorescent video microscopy images of cell
mitosis (Ted Salmon)
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SUCCESSES Roadmap Planning Grant or other Awards

• PI Theme Department/Center
• B. Popkin Obesity Population Center
• R. Rindfuss Land Use Health Population Center
• B. Sartor Imaging Inflammation Medicine
• D. Reed/ Exploratory Genetics Computer Sci/
• T. Magnuson Genetics
• G. Johnson Nanomedicine Pharmacology
• H. Guess Patient Outcomes Public Health

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• WHAT NEXT?
• LOOKING FOR A FEW
• GOOD MEN/WOMEN
• 2. DARE TO DREAM BIG DREAMS

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• Help the Roadmap at UNC
• Consider leading a Roadmap or Roadmap-Like
  proposal.
• Let us know about it!!
• 2. Help us to penetrate the NIH. Are you on NIH
  Council?
• Study Section? Advisory Group? Let us know about
  it!!