Deans Workshop on Biomedical Engineering

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Deans Workshop on Biomedical Engineering

• Biomedical Engineering at Yale
• Collaborations and Translational Partnerships
• W. Mark Saltzman

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Where did we come from? Who are we now? Where do
we want to be? My perspective on todays program
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Where did we come from? Who are we now? Where do
we want to be? My perspective on todays program
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Biomedical Engineering at YaleResearch and
Educational Strengths
Biomolecular engineering
Bioimaging
Biomechanics
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Richard Carson, PET imaging and modeling Todd
Constable, MR imaging James Duncan, Image
analysis/processing Fahmeed Hyder, MR
spectroscopy Michael Levene, Biophotonics/optical
microscopy Douglas Rothman, MR
spectroscopy Lawrence Staib, Image
analysis/processing Steven Zucker, Computer
vision Jacek Cholewicki, Spine biomechanics
Tarek Fahmy, Targeted drug delivery Erin Lavik,
Tissue engineering Mark Saltzman, Drug
delivery/tissue engineering
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Hemant Tagare, Diagnostic Radiology Xenios
Papademetris, Diagnostic Radiology Robin
deGraaf, Diagnostic Radiology Steven Segal,
Physiology/Pierce Themis Kyriakides , Pathology
Fred Sigworth, Physiology Mark Laubach,
Neurobiology/Pierce Laura Niklason,
Anesthesiology Francesco dErrico, Diagnostic
Radiology
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Biomedical Engineering at YaleResearch and
Educational Strengths
Biomolecular engineering
Bioimaging
Biomechanics
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Where did we come from? Who are we now? Where do
we want to be? My perspective on todays program
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(No Transcript)
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Where did we come from? Who are we now? Where do
we want to be? My perspective on todays program
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1 Imaging is central to Biomedical Engineering
research
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Biomedical Imaging at Yale
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Image-guided neurosurgery for epilepsy Jim
Duncan, Dennis Spencer et al.
fMRI
Left hand (red/yellow) right hand (blue) motor
cortex activation
MRS
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Multiphoton in situ histology, Michael Levene
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Francesco dErrico, Dept Diagnostic Radiology
Microemulsions for ultrasound-controlled drug
release
Concept of image-guided drug release with
ultrasound sensitive microemulsions
Doppler imaging of rabbit kidney whereby the
vaporization of droplets in the renal artery
reduces the blood flow
Perflurocarbon droplets with oil inclusions
containing a water-insoluble drug
The blood flow is gradually restored when bubbles
dissolve in the blood-stream
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2 Biomolecular Engineering provides new
opportunities for basic and translational research
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Nanoparticles for Controlled Release of
CurcuminMargaret Cartiera, Mark Saltzman, Marie
Egan, Michael Caplan
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Nanoparticles particles as small as a virus, but
engineered from safe synthetic polymers and
loaded with high concentrations of drugs
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Microengineered Scaffolds to Guide Cell
Development to Tissues
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3 Collaboration and translation
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One biomedical engineers experience at Yale
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Opening Remarks Carolyn W. Slayman, Ph.D. Deputy
Dean for Academic and Scientific
Affairs 130-200 PM BIOMEDICAL ENGINEERING AT
YALE COLLABORATIONS AND TRANSLATIONAL
PARTNERSHIPS W. Mark Saltzman, Ph.D. Goizueta
Foundation Professor of Chemical and Biomedical
Engineering and of Cellular and Molecular
Physiology 200-230 PM TOWARDS THE CONSTRUCTION
OF NEW GENERATION VACCINE SYSTEMS BASED ON
BIOLOGICAL-DRIVEN DESIGNS Tarek Fahmy,
Ph.D. Assistant Professor of Biomedical
Engineering Ira S. Mellman, Ph.D. Sterling
Professor of Cell Biology and Professor of
Immunobiology 230-300 PM BRINGING MULTIPHOTON
MICROSCOPY TO THE CLINIC ASSESSMENT OF WOUND
HEALING WITH ARTIFICIAL SKIN GRAFTS AND OTHER
APPLICATIONS Michael J. Levene, Ph.D. Assistant
Professor of Biomedical Engineering Jordan S.
Pober, M.D., Ph.D. Professor of Pathology,
Immunobiology and Dermatology 300-330
PM ARCHITECTURAL HYDROGELS SCAFFOLDS FOR
VASCULAR AND NEURAL PROGENITOR CELL CONSTRUCTS
FOR THE NERVOUS SYSTEM Erin Lavik,
Sc.D. Assistant Professor of Biomedical
Engineering Joseph A. Madri, M.D.,
Ph.D. Professor of Pathology and of Molecular,
Cellular and Developmental Biology
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