Title: Anthrax the sequel
1Click for larger picture
Modified from N.Y. Dept. of Health
2Anthrax as a Biological Weapon (JAMA. 1999
2811735-1745)
Figure 4. Day of Onset of Inhalational Anthrax
Following Sverdlovsk Accident Figure is based on
data from Guillermin.68
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This curve approximates that of the accumulated
deaths more closely
(JAMA. 1999 2811735-1745)
4Lidia Tretyakova looks at the tombstone of her
father, Lazar Karsayev, at a cemetery in
Yekaterinburg, Russia, Thursday, Oct. 18, 2001. A
mysterious outbreak of anthrax killed at least 68
people, including Karsayev, 22 years ago in the
Russian industrial center of Sverdlovsk, today
known as Yekaterinburg. At the time, neither the
victims nor their families suspected they had
been hit by a biological weapon.
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6Laboratory workers at the Sverdlovsk regional
epedemiological service put on the special suits
they wear when working with anthrax and other
dangerous bacteria in Yekaterinburg, Russia,
Wednesday, Oct. 17, 2001
7A general view of the Stepnogorsk Scientific
Experimental and Production Base (SEPB) in
Stepnogorsk, 220 km (100 miles) northwest of
Kazakstan's new capital of Astana, Monday, Oct.
22, 2001. The SEPB was the biggest
anthrax-manufacturing plant in the world.
(AP Photo)
8Scientists work in an environmental monitoring
laboratory of Stepnogorsk Scientific Experimental
and Production Base (SEPB) in Stepnogorsk, 220 km
( 100 miles) northwest of Kazakstan's new capital
of Astana, Monday, Oct. 22, 2001. The SEPB was
the biggest anthrax-manufacturing plant in the
world. (AP Photo)
9Review of some Consensus guidelines
J.A.M.A.1979. 281 1735-1745. Working Group on
Civilian Biodefense
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J.A.M.A.1979. 281 1735-1745. Working Group on
Civilian Biodefense
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J.A.M.A.1979. 281 1735-1745. Working Group on
Civilian Biodefense
Ratified in MMWR. 2001. 50 889-897. (Oct. 19,
2001)
12The recent Anthrax victims
- The victims of the recent terrorist use of
anthrax bacilli started to appear in October
2001. On October 2 the spinal fluid of a patient
in Miami showed large Gram positive bacilli,
confirmed on October 4 as Bacillus anthracis
13 Ottilie Lundgren, 94 Inhaled Connecticut
farm Died, Nov.21, 2001
List of recent bioterrorism-related Anthrax
victims
Norma Wallace, 56
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Data mostly from Jernigan et al., Emerging
Infectious Diseases, 7 933-944, 2001 Patient
No. 11 is not presented in the Jernigan series
the data appeared in the news.
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22Timeline of 10 cases of inhalational anthrax in
relation to onset of symptoms, October through
November 2001
Click for larger picture
Jernigan et al., Emerging Infectious Diseases, 7
933-944, 2001
23Table 2, Jernigan et al., 2001. Emerging
Infectious Diseases, 7 933-944.
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Table 3, Jernigan et al., 2001. Emerging
Infectious Diseases, 7 933-944.
25Initial chest X-ray, Case 1 Prominent upper
mediastinum
26Gram stain, cerebrospinal fluid, Case 1 ? Clear
diagnosis, Oct. 2, 2001
27Chest X-ray, Case 2 Diffuse consolidation,
consistent with pneumonia of left lung No
mediastinal widening
28Computed tomography of chest, Case 2 Bilateral
pulmonary consolidation and pleural effusioins
29Chest X-ray, Case 7 Mediastinal widening, left
pleural effusion
30Chest computed tomography, Case 7
Mediastinal adenopathy,
bilateral pleural effusions