Title: SA node
1(No Transcript)
2(No Transcript)
3(No Transcript)
4????? ??????
- SA node
- ?????
- AV node
- Bundle of His
- ??? ????????
- ?????
5????? ????? - ?????
6????? ????? ????? ?????
7????? ????? - ?????
8?????? ????? ??????
- ???????? ????????? ?? ??????
- ????? ?- AV node
- ???????? ????????? ?? ??????, ???? ???? ????????
??????.
9?????? ?????
- ????? 0.5 m/sec
- AV node 0.05 m/sec
- Bundle of His 2 m/sec
- ??? ???????? 4 m/sec
- ????? 0.5 m/sec
10???????? ????? ????? ?????
11(No Transcript)
12???????? ????? ?????????? ?????
13When these cells are rapidly depolarized to a
threshold voltage of about -70 mV (e.g., by
another conducted action potential), there is a
rapid depolarization (phase 0) that is caused by
a transient increase in fast Na-channel
conductance. At the same time, gK falls. These
two conductance changes move the membrane
potential away from EK and closer toward ENa.
Phase 1 represents an initial repolarization that
is caused by the opening of a special type of K
channel (not shown in the figure). However,
because of the large increase in slow inward
gCa, the repolarization is delayed and there is
a plateau phase in the action potential (phase
2). This inward calcium movement is through
long-lasting (L-type) calcium channels that open
up when the membrane potential depolarizes to
about -40 mV. Repolarization (phase 3) occurs
when gK increases and gCa decreases.
Therefore, the action potential in non-pacemaker
cells is primarily determined by changes in fast
Na, slow Ca and K conductances as summarized
below and in the figure to the right.
14???????? ????? ?????????
???????? ????? ?????, ?????????? ??? ???
???????? ?????
??? ????? ??????????
15???????? ????? ?????, ?????????? ??? ???
???????? ?????
16???
17???
18?.?.?.
- ????? ????. ?? ???? ??????.
- ????? ????? ?
- ?????? ????? ?? ???
- ???? ??????
- ???? ?????
- ????
- ??????????
- ?????
19???? ????
20?.?.? ????????? ????? ????
21???????? ????? ????, ??.?.?.
22???? ??.?.?.
- ?? P ?????????? ??????
- ???? ?? P ???? ???????? ????? (???? ?????
?????) - ?? QRS ?????????? ??????
- ?????? ????? ?????? ?????? ????? ??? ?????????
- ?? T ?????????? ??????
23??????? ??.?.?.
- ????? PR (PQ) ??? ????? ??? ????? ??????
- ????? ????? ????? ?????? ?- AV node
- ????? QT ??? ???????? ????? ????
- ????? PP ??? ??????
- ????? QQ ??? ??????
24EKG ????? ?????
25?????
26EKG ?? ????
27????? ?????
SA node ????? ? -