HDL-Atherosclerosis Treatment Study (HATS): Lipid Results

1
HDL-Atherosclerosis Treatment Study(HATS)
Lipid Results
Placebo Simvastatin niacin (SN)
Antioxidant vitamins (AV) SNAV
plt.05 vs baseline
Change,














TC
LDL-C
HDL-C
HDL2-C
TG
Lp(a)
Brown BG et al. N Engl J Med 20013451583-1592.
2
HATS Angiographic and Clinical Endpoints
Placebo
SN
AV
SNAV
25 20 15 10 5 0
90 reduction
3.9
23.7
21.4
plt.05 vs placebo
14.3
Composite Event Rate,
Change in Stenosis,
1.8


0.7
2.6

-0.4
Coronary Death, MI, Stroke, or Revascularization
9 Proximal Lesions
Brown BG et al. N Engl J Med 20013451583-1592.