CLOPIDOGREL PATHWAY - PowerPoint PPT Presentation

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CLOPIDOGREL PATHWAY

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Heme. Cyclic AMP. HMDB00058. Adenosine Triphosphate. HMDB00538. Adenylate Cyclase. Q96PN6 ... Heme. Cytochrome P450. 3A4. P08684. Heme. Active Metabolite ... – PowerPoint PPT presentation

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Title: CLOPIDOGREL PATHWAY


1
CLOPIDOGREL PATHWAY In Homo sapiens
Clopidogrel DB00758
2-Oxo-clopidogrel
Cytochrome P450 1A2 P05177
Cytochrome P450 2C9 P11712
Cytochrome P450 3A4 P08684
Heme
Heme
Heme
SUBENDOTHELIUM
ACTIVATION
Integrin beta-1 P05556
Integrin alpha-2 P17301
Thrombin P00734
ACTIVATION
 Phospholipase A2, membrane associated P14555
Ca2
Thomboxane-A synthase P24557
Heme
ACTIVATION
Heme
Heme
Zn
Cyclic AMPHMDB00058
INHIBITION
ACTIVATION
 1-phosphatidylinositol- 4,5-bisphosphate
phosphodiesterase delta-4 Q9BRC7
ACTIVATION
Ca2
ACTIVATION
ACTIVATION
Mg2
ACTIVATION
Adenylate Cyclase Q96PN6
INHIBITION
ACTIVATION
ACTIVATION
ACTIVATION
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