Research Presentation

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Research Presentation Nordborg Lab University of
Southern California
Helly Kwee August 21, 2003 Southern California
Bioinformatics Summer Institute
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Agenda

• Research area overview
• Projects
• Bioinformatics Tools
• Current State of Affairs
• Conclusion (Impacts)

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Overview

• Genetic basis of adaptation
• Map loci conferring natural variation in
  Arabidopsis thaliana
• NSF 2010 Project

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Projects

• Genomic survey of polymorphism in A. thaliana
• Sequence 2000 fragments from 96 accessions
• Phenotype various traits
• Association analysis
• Bioinformatics tools
• Publicly accessible database
• Web-based viewers

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Bioinformatics Tools

• Revised database schema
• Populating the database
• Revised web-based viewers
• Genome
• Polymorphism
• Alignment

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Database Contents
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Code Revision I
Modules
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Screenshot Genome Viewer
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Screenshot-- Polymorphism Viewer
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Impacts

• Insights into genetic basis of natural variation
• Genes responsible for agriculturally important
  traits
• Tools and methods --gt applicable to economically
  important organisms
• Database as training tool

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Questions
?
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Acknowledgements

• Dr. Nordborg and his lab
• SoCalBSI faculty
• NSF and NIH