Title: Content for 110 genes uploaded
1Content for 110 genes uploaded
2(No Transcript)
3Interesting literature mined genes with regional
enrichment
Pleiades region Genes Cerebral cortex Satb1,
Satb2, Nxph3, Mef2c Hippocampus Gria1, Gabrd,
Hmg1, Ulk1 Ependymal Ccnd2, Dlx1 Striatum Str
n, Rgs9, B3gnt1 Amygdala Grp, Prlr,
Cd24a Thalamus Isl1, Rgs16, Nr2f1 Hypothalamus
Avp, Agt, Pitx2 Cerebellum white matter Apod,
Mbp, Mag, Mobp Cerebellum purkinje Dao1, Gdf10,
Grid2 Basal nucleus of Meynert - Substantia
nigra Lbh, Msi2h, Drd2 Raphe nuclei Slc17a8,
MaoA, MaoB Locus coeruleus Sc5d, Slc6a2,
Fgfr1
4Interesting literature mined genes with regional
enrichment
GSK region Genes Thalamus Isl1, Rgs16, Nr2f1
Hypothalamus Paraventricular
nucleus Trh, Cart Brainstem
Pons Fgfr1, Cyp51, Anxa4, Fabp3
Medulla Anxa4, Dbh, Pou4f1 Somatosensory
cortex Anterior cingulate cortex Periaqueductal
grey Trh Barringtons nucleus Rostroventromedial
medulla
5SAGE mined genes with interesting AIBS expression
patterns
6Mef2c Primary motor cortex restricted expression
Lyons GE et al. 1995. J. Neurosci. 155727-5738
Sage GS strategy 46
7Satb2 Visual cortex restricted expression
Rat cortex immunostain
Szemes M et al. 2006 Neurochem Res.
31(2)237-46.
Sage GS strategy 91
8Sstr4 Hippocampus CA1 restricted expression
Sage GS strategy 4
9Gria1 Hippocampus CA1 and dentate gyrus
restricted expression
Chun HS et al., 2003. Neuroreport. 14(7)1055-9
Sage GS strategy 55
10Mlf1 Ependymal layer restricted expression
Hitzler, JK et al, 1999. Am J Pathol.
155(1)53-9.
Sage GS strategy 1
11Rgs9 Striatum restricted expression
Thomas EA et al, 1998. J. Neuroscience research
52(1)118-24.
Sage GS strategy 51
12Cyp26b1 Amygdala basolateral and central nucleus
restricted expression
Sage GS strategy 19
13Grp Amygdala basolateral restricted expression
ISH
Shumyatsky GP et al, 2002. Cell. 111(6)905-18
Sage GS strategy 45
14Slitrk6 Thalamus (ventral enriched) expression
Sage GS strategy 7
15Rgs16 Thalamus (medial and ventral) restricted
expression
Grafstein-Dunn E et al. Brain Res Mol Brain
Res. 2001 88113-23.
Sage GS strategy 21
16Trh Hypothalamus restricted expression
Legradi G et al. 1997. Endocrinology.
138(6)2569-76
Sage GS strategy 9
17Mobp White matter restricted expression
Montague P et al, 1997, J. Neurosci. Res.49133
-143
Sage GS strategy 53
18Gdf10 Cerebellar purkinje restricted expression
ISH
Sage GS strategy 1
19Lanc13 Basal nucleus of Meynert restricted
expression ???
Sage GS strategy 9
20Th (Tyrosine hydroxylase) substantia nigra
restricted expression
Sage GS strategy 5
21Chrna6 Substantia nigra restricted expression
Sage GS strategy 1
22Gnas Locus coeruleus and raphe nucleus
expression
Sage GS strategy 59
23Slc6a2 Locus coeruleus restricted expression
Sage GS strategy 91
24Slc6a4 Dorsal raphe nucleus restricted
expression
Sage GS strategy 2
25Literature mined genes of significant interest
but not on the SAGE 2000 list
26Mbp White matter restricted expression
27Pomc1 Hypothalamus restricted expression