Genetics of Pulmonary fibrosis

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Genetics of Pulmonary fibrosis

• John A. Belperio, M.D.

UCLA School of Medicine, Division of Pulmonary
and Critical Care Medicine
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Genetics of Pulmonary fibrosis

• Exclude collagen vascular disease

Exclude occupational disease
Exclude medications associated with pulmonary
fibrosis
Clustering of pulmonary fibrosis seen in families
IPF seen in separately raised monozygotic twins
IPF seen in more than two generations in several
studies, and in several father son pairs