JetGuide Ltd'

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Real-Time Bone Drilling Monitoring February
2008
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The Team

• Jacob Halevy-Politch, D.Sc., E.E.,
  CEOTechnionIsrael Institute of Technology,
  Rafael Israel Armaments Development Authority,
  Israel Air Force
• D. Todd Dollinger, ChairmanJetGuide board, The
  Trendlines Group
• Prof. Dan AdamDepartment of Biomedical
  Engineering, Technion-Israel Institute of
  Technology
• Andrei Craft, D.D.S. Oral and maxillofacial
  surgeon, formerly Rambam Medical Center (Israel)
  and Toronto University Dental School
• Dr. Nahum Rosenberg, M. Ortho.Orthopedic
  Department, Rambam Medical Center
• Steve RhodesCEO, Misgav Venture Accelerator, and
  Chairman, The Trendlines Group

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Blind Mans Bluff
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Vision and Markets
Safe and Accurate Bone Drilling

• Orthopedic/spine
• gt6 growth
• gt30 billion
• Other surgical growth rates up to 15
• ENT 5 billion
• Neurosurgery spine and skull 6 billion
• Plastic surgery 5 billion
• Oral surgery
• 2 million implants performed annually 2.4
  billion
• Growth 15-18
• Untapped market implants 10 of tooth
  replacements

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Value Proposition
Surgeons
Real-time intraoperative feedback during surgery
builds confidence and raises comfort levels. More
surgeons can perform procedures.
Healthcare payors
Reduction in complications for decreased costs
Patients
Improved outcomes andfaster procedures
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The JetGuide Dental System

• Implantology

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How It Works

• Water-Guided Ultrasonic Waves

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Competition
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Competitive Advantages

• Accurate
• Real-time
• Simple to use
• Safe
• Affordable
• Compact

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Business Development
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Achievements

• IP
• Patents strategy patents applied for
  continuing applications
• Technology/Science
• Operating system, algorithms, display, ultrasound
  cell operational
• Successful experiments on phantoms and ex-vivo
  fresh animal bones
• IRB and Ministry of Health approvals for human
  trials
• Clinical trials under way Rambam Medical
  Center, Haifa
• Business Development
• Established Scientific Advisory Board
• On-going talks with leaders in ortho and dental
  markets
• Regulatory
• FDA pre-ruling received
• Regulatory strategy, filing in process

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Scientific Advisory Committee

• Professor Nachum SametAssistant Professor of
  Restorative Dentistry Biomaterials Sciences,
  Harvard School of Dental Medicine
• Professor M. SilbermannFormer Chief Scientist,
  Ministry of Health Dean, School of Medicine,
  Technion-Israel Institute of Technology Chair,
  Dept. of Anatomy
• Professor Peter BirekInternationally recognized
  expert in dental Implantation and Osseo
  integration Dental School, the Univ. of Toronto,
  Canada.
• Professor M. ZaarurChief, Dept. of Neurosurgery,
  Rambam Hospital School of Medicine, Technion
• Dr. Micha Peled, M.D., D.D.S.Chief, Oral and
  Maxillofacial Surgery, Rambam Hospital School of
  Medicine, Technion-Israel Institute of Technology

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Financial Projections
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Opportunity

• JetGuide seeks 2 million for
• Advanced product development
• Clinical trials
• Initial production
• Business development
• JetGuide Ortho new markets

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JetGuide Ltd.

• Jacob Halevy-Politch, CEO
• JetGuide Ltd.
• Telephone [phone]
• E-mail yapo_at_jet-guide.com
• Web www.jet-guide.com

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Development Plan
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About JetGuide

• September 2005 joined Misgav Venture
  Accelerator
• Funding to Date
• The Office of the Chief Scientist of the Israel
  Ministry of Industry, Trade Labor
• The Trendlines Israel Fund
• Founders