Graves Disease or Taverna in VLe

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Using myGrid for Science
myGrid technologies provide infrastructure for
scientific investigation. Here we present
examples
of current projects using myGrid.
Life Sciences
Graves Disease or Taverna in VL-e
Peter Li, University of Newcastle,
Identify I kappa B-epsilon as a candidate gene
involved in Graves disease using Microarray data
and workflows built with Taverna.
MCISB www.mcisb.org/ At the Manchester Centre for
Integrative Systems Biology, Tavernas workflows
are used to integrate heterogeneous data and
databases associated with Saccharomyces
cerevisiae (yeast).
SIGENAE, France The Information System of AGENAE
group uses Taverna To provide services to
biologists working on 8 species (cattle, chicken,
pig, rabbit,sheep, trout, oyster, sea bass and
sea bream). www.sigenae.org/index.php?id84
Genotype/phenotype correlations Paul Fisher,
University of Manchester, identified new
candidate genes and new pathways involved in
trypanosome resistance that had previously been
missed by traditional methods, showing the
advantages of the systematic workflow
approach. http//www.cs.man.ac.uk/fisherp/
Astronomy
Chemistry
Health Informatics
PsyGrid www.psygrid.orgProvides clinical trials
infrastructure using workflows and other myGrid
components to support the handling of patients
with first episode psychosis.
Astrogrid www2.astrogrid.org/ Enable astronomers
to access a Virtual Observatory. Use Taverna as
workflow engine for the Virtual Observatory.
CDK-Taverna, University of Cologne Integrated
Pipelining Technology combining Taverna,
Bioclipse and the CDK (The Chemistry Development
Kit ). http//cdk.sf.net
MIAS-Grid Provides a Grid platform for medical
imaging and signals research built on myGrid
technologies. www.robots.ox.ac.uk/irc/grid_mias-g
rid.html
SAMPO http//www.eso.org/sampo
Taverna is being used as a
workflow engine for astronomical data reduction
at the European Southern Observatory
Chimatica www.chimatica.co.uk Virtual drug
candidate production environment. It uses
workflows built with Taverna to target molecule
identification.
www.mygrid.org.uk for more projects
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myGrid Supporting scientific workflow with
Taverna
myGrid
Scientific provenance
A provenance log shows which workflows were run
at which time, and enables rerunning workflows so
the scientists can validate their results.
myGrid is a UK e-Science project that provides
software components to support data-intensive, in
silico experiments, Predominantly in the Life
Sciences.
Service discovery
Challenges
Taverna provides a semantic discovery tool Feta,
which allows users to search web services by
task, input and output description, etc.
Bioinformatics data in the public domain is vast,
heterogeneous and distributed throughout the
world. While the public availability has enabled
great advances in the field, the heterogeneity
and distribution means using these resources
together can be problematic.
Taverna has a tree-based interface
Taverna Workbench
myGrid enables the interoperation between
Bioinformatics services and database by providing
a toolkit for composing, executing and managing
workflow experiments. Taverna is the workflow
environment of myGrid, which allows the
coordinated interconnection between distributed
resources. Taverna can use virtually any
WSDL-described web services in its workflow, and
internally the API is open for extensions for
plugins.There are over 3000 web services known to
work with Taverna.
Taverna workflow result panel.
Sharing and collaboration
Acknowledgements
Workflows created by Taverna can be reused and
repurposed within the myGrid community. myGrid is
developing the science portal, myExperiment, with
focus on collaborative composing and discovery of
services and Workflow fragments.
Project director Professor Carole
Goble Acknowledgment list www.mygrid.org.uk/wiki/
Mygrid/Acknowledgements
A Taverna workflow for analysing QTL
information in relation to microarray
probesets.
www.mygrid.org.uk
www.mygrid.org.uk