Brugadas Syndrome

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Brugadas Syndrome
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Brugadas Syndrome

• First described at the U. of Barcelona in 1992
• Autosomal dominant with variable expression
• Potentially fatal arrhythmias
• ventricular fibrillation
• torsades de pointes
• Hx of syncope or aborted sudden death
• Usually become symptomatic in childhood or young
  adulthood

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Brugadas Syndrome

• Unique ECG findings
• right bundle branch block
• ST elevation in leads V1-V3
• DDx acute MI with RBBB
• Provacative tests in the CCU
• iv procainamide elicits the ST elevation
• Treatment
• automatic implantable defibrillator

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Brugadas Syndrome

• Mortality due to sudden death
• pts
• AICD 0 35 BB or CCB 26 15
• No treatment 31 13

Circulation 1998975457-60