Laboratory Automation

1

• Laboratory Automation Instrumentation Power
  Protection Systems
• Case Study
• Celera Genomics

2
Celeras Benefits

• Lower Operating Cost
• Increased Productivity
• Happier Investigators/Managers/Staff
• Higher Revenue Investor Potential

3
The Lab and OperatingEnvironment

• Key challenges and issues
• Profitability in the laboratory and automation
  environments
• On time delivery of reportable results
• Overall customer satisfaction
• Internal and external

4
The Lab and OperatingEnvironment

• Key issues and distracters
• Instrumentation performance
• Human Genome race
• Availability and reliability
• Environmental conditions

5
The Laboratory

• Key issues - Environmental
• Quality of power from the utility
• Other equipment sharing the line
• Centrifuges
• Auto loaders / robotics
• Pumps and heaters
• Bar code readers (lasers)
• Other PCR-DNA Sequencing Instrumentation

6
The Laboratory

• Quality of power directly from the utility
• Desired waveform

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The Laboratory

• The reality of laboratory and production power
• Harmonic distortion and frequency variation
  waveform is typical
•  

Power Interrupt Line Sag Surge Under Voltage Over Voltage Line Noise Variable Frequency Switching Transient Harmonic Distortion
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The Lab and OperatingEnvironment

• Key issues - Environmental
• Challenges for a Laboratory Productivity-Protectio
  n System (LPS)
• Each application must be qualified
• Peak loads
• Other instrumentation line interference
  (transient)
• Inrush currents and load (Power) factors
• Power connection and distribution
• Waveform (Volts, Hz, harmonic distortion, et al)

9

• Franek Technologies, Inc. (FTI)
• The Leader in
• Power Protection for
• Medical and Scientific Instrumentation

10
Applications

• Automation
• Biotechnology
• Drug discovery
• DNA, human Genomics and Proteomics research
• Pharmaceutical production
• Clinical chemistry
• Diagnostic imaging
• Immunology and cytometry
• Oncology
• Hematology and blood banking
• FDA 510(k) patient contact applications
• Forensics
• Scientific research
• Other commercial laboratory instrumentation

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Key Applications

• Several Billions in Protected
• Laboratory and Production Instrumentation
• Baxter Healthcare
• Over 1,800 LPS placements worldwide
• Celera Genomics
• 320 LPS placements in a single Lab
• Mallinckrodt (Nellcor / Puritan-Bennett)
• Over 200 FDA 510(k) Ventilator support patient
  contact

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Key Applications

• Several Billions in Protected
• Laboratory Instrumentation
• Perkin Elmer / ABI, DNA Protein Analyzers
• Over 3,000 LPS placements worldwide
• Datex Ohmeda, Drager and North American Drager
• Over 200 510(k) LPS units for anesthesia work
  stations

13
Franek Value

• Cutting Edge Technology
• Engineered Qualified Application Program
• Most Qualified and Experienced of all Power
  Protection Firms
• Laboratory
• Pharmaceutical
• Healthcare Research
• Scientific markets

14
LPS Economics

• LPS Application Rules of Thumb
• LPS systems are very affordable
• Service costs are 2,000 / Hr, or more
• LPS systems have proven ROI
• Instrumentation operating costs drop
• Instrumentation availability is very high
• Overall productivity is maximized
• Instrumentation and internal customer
  satisfaction performance improves

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FTI Case Studies

• Celera Genomics Corporation
• race with Human Genome Project Several
  billions invested
• Goals
• First to patent the human genome Time Critical
  Race
• Strategy
• Develop subscription based business to genome
  database
• Partner with major pharmaceutical clients for
  drug discovery
• Challenges
• Maintain genome sequencing focus
• Keep the Rockville, MD and Foster City, CA labs
  operational
• Sequence in PE/ABI analyzers as development
  schedule required
• Operate nearly 350 DNA Sequencer systems
  simultaneously

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FTI Case Studies

• Celera Genomics Corporation
• race with Human Genome Project Several
  billions invested
• Laboratory Challenges and Issues
• Keep the Rockville, MD and Foster City, CA labs
  operational
• Sequence in PE/ABI analyzers as development
  schedule required
• Operate nearly 350 DNA Sequencer systems
  simultaneously
• Minimize laboratory infrastructure while
  maintaining effectiveness
• Strategy
• FTI Consulted as laboratory power engineering
  specialists
• FTIs five year partnership with PE/ABI lead to
  sole source orders
• Challenges
• LPS system design to assure DNA Sequencer
  operational integrity
• LPS Lab engineering modifications unique to
  the lab environment
• Delivery and servicing of over 325 LPS units in 9
  months

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FTI Case Studies

• Celera Genomics Corporation
• race with Human Genome Project Several
  billions invested
• Celera and PE/ABI Results
• Celera claimed victory in genome discovery
• Kept Rockville, MD and Foster City, CA labs
  operational
• Established PE/ABI and FTI as key business
  partners
• Researchers provided FTI referrals to all lab
  types
• CDC, NIH, University, Pharmaceutical, Forensic
• All economic goals for Celera and PE/ABI attained
• Estimated savings for Celera at over 24 Million

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FTI Case Studies

• Celera Genomics Corporation
• Detailed Analysis
• FTI cost savings for Celera and PE/ABI (Goals)
• Prevented .10 failure / instrument / 24 hour
  period (minimum)
• 350 systems _at_ 365 days 127,750 operational days
• Potential operational incidents 12,775
• Down time cost per incident 2,000.00
• Potential down time savings 25,550,000
• Benefit to Cost 131

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Engineered Laboratory Instrumentation
Protection Systems
www.franek-tech.com 800 326 6480 / 1 714 734
5656