Drugs for Hematopoietic and Respiratory Disorders

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Drugs for Hematopoietic and Respiratory Disorders

• Julie Balk MS, APRN
• NSG 220
• March 2007

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Hematopoiesis

• Hematopoietic stem cell (from red bone marrow)
• Magakaryoblast
• Thrombopoietin, Interleukin-II
• Platelets
• Leukocyte stem cell
• Colony-stimulating factors
• Macrophages
• Granulocytes
• Erythrocyte stem cell
• Erythropoietin
• Erthrocytes

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Hematopoietic Growth Factors

• Prototypeepotein alfa (Epogen)
• Mechanism of Action
• Nursing Considerations

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Hematopoietic Growth FactorsColony Stimulating
Factors

• Prototype filgrastim (Neupogen)
• Mechanism of action
• Nursing Considerations

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Antianemic Agents

• Classification of Anemia
• Based off description of erythrocytes size and
  color
• Prototype drug cyanocobalamin B12
• Mechanism of Action
• Nursing Considerations

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Antianemic Agents

• Prototype Drug ferrous sulfate
• Mechanism of Actions
• Nursing Considerations

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Disorders of the Respiratory System

• Asthma
• Upper Respiratory Tract Infection (common cold)
• Chronic Obstructive Pulmonary Disease (COPD)

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Drugs Used for Asthma

• Beta Agonists/Sympathomimetics
• Prototype Drug salmeterol (Serevent)
• Mechanism of Action
• Nursing Considerations
• Anticholinergic
• Prototype Drug ipatropium bromide (Atrovent)
• Mechanism of Action
• Nursing Considerations

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Drugs Used for Asthma

• Glucocorticoids
• Prototype Drug beclomethasone (Beclovent)
• Mechanism of Action
• Nursing Considerations

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Drugs Used for the Common Cold

• Antitussives
• Prototype Drug dextromethorphan (Pedia Care)
• Mechanism of Action
• Nursing Considerations

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COPD

• Asthma
• Chronic bronchitis
• Emphysema
• Pharmacologic Management
• Symptomatic relief
• Treat Infections
• Control Cough/secretions