Similar to NFkB

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Similar to NFkB
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Zn finger
23 a.a.
7-8 a.a.
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C-term
N-term
DNA binding sites
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Deletion of C-term. Region leads to
constitutively active protein.
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Ligand binding changes shape of receptor
and releases corepressor so coactivators can now
bind.
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DNA Methylation and Transcriptional Regulation
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Stages of Regulation
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