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Evaluation of Post-Trabeculectomy Visual Function Using Orbscan

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Tadashi Nakano MD1 Takahiko Noro MD1. Hideki Matsuda MD1 Yoshinori Itou MD1 ... 1. Rosen WJ, Mannis MJ, Brandt JD : The effect of trabeculectomy on corneal topography. ... – PowerPoint PPT presentation

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Title: Evaluation of Post-Trabeculectomy Visual Function Using Orbscan


1
Evaluation of Post-TrabeculectomyVisual Function
Using Orbscan
  • Kozue Kasai MD1
  • Tadashi Nakano MD1 Takahiko Noro MD1
  • Hideki Matsuda MD1 Yoshinori Itou MD1
  • Masayuki Tatemichi MD2 Hiroshi Tsuneoka MD1

1 The Jikei University School of Medicine
Department of Ophthalmology 2 Showa University
2
Purpose
  • 1. To evaluate changes in corneal topographic
  • characteristics of patients
  • after trabeculectomy (LEC).
  • 2. To study the relationship of central corneal
  • thickness using Orbscan.

3
Methods and Patients
Post-trabeculectomy group with OAG 24
eyes Control group 16 eyes (nonoperated
eyes of post-LEC patients or volunteer
eyes) TOTAL 40 eyes (24 patients were
examined with Orbscan at our glaucoma outpatient
clinic)
4
Methods
Post-LEC group 20 patients 24 eyes Control group 13 patients 16 eyes p value
Age (years) 58.815.2 67.35.6 0.580
Sex (man / woman) 11 / 9 8 / 5 0.508
Visual acuity (log) 0.600.58 1.000.17 0.001
Spherical equivalent D -3.723.45 -1.143.50 0.001
Corneal astigmatism D -1.590.96 -0.800.50 0.004
Tonometry mmHg 11.44.72 16.35.64 0.009
Corneal thickness ?m 55638.6 55843.7 0.978
Postoperative period months 48.151.3
NIDEK ARK-700A Mann-Whitney U-test
5
ORBSCAN ver 3.0Evaluation items
  • Using an illuminated ring pattern and a beam of
    light,
  • Orbscan shows surface power and the front and
    back shapes.
  • Not effected by eye dryness. Time less than
    2 seconds

Using two groups (3-mm and 5-mm zone irregularity
ZI)
Mean power The average of the maximum and
the minimum of the cornea refractivity in the
arbitrary measurement point astigmatic power
The difference of the maximum and the minimum of
the cornea refractivity in the arbitrary
measurement point
6
Methods
1. Zone Irregularity
5-3-mm ZI Difference between 5-mm ZI and 3-mm ZI
(5-3-mm ZI) as an index of the peripheral area
3-mm ZI Central corneal Irregularity miosis
(daytime condition)
5-mm ZI Corneal irregularity of paracentral
quadrants mydriasis (night condition)
2. Corneal thickness
Corneal thickness was measured by Orbscan
slit scan pachymetry. A representation of the
central corneal thickness. (within a 3-mm
circle from the center)
7
Results 1 Irregularity vs treatment

Irregularity


Post-LEC Control
Post-LEC Control
Post-LEC Control
3-mm Zone
5-mm Zone
5-3-mm Zone
Mann-Whitney U-test
P lt 0.5 P lt 0.01 P lt 0.001
Irregularity was greater in the Post-LEC group
than in the control group in all zones.
8
Results 2 Irregularity vs Corneal thickness
Irregularity

12

10

8
6
4
2
0
lt540 ?m ?540 ?m
lt540 ?m ?540 ?m
lt540 ?m ?540 ?m
3-mm Zone
5-mm Zone
5-3-mm Zone
Mann-Whitney U-test
P lt 0.5 P lt 0.01 P lt 0.001
Irregularity was greater with corneal thickness lt
540?m than with corneal thickness ?540 ?m in the
zones.
9
  • Report of Evaluation of Post-trabeculectomy
  • 1. Video-keratoscopy
  • After LEC, the peripheral parts of the cornea
    near the scleral flap area become steep.
  • After LEC, visual acuity decreased with
    topographic changes near the scleral flap.
  • 2. TMS-1 TMS-2 Video-keratoscopy
  • After LEC, there are no changes in SRI or SAI
    as indexes of astigmatic irregularity.
  • 3. TMS-1
  • After LEC, The steep area around the cornea
    does not influence the corneal center.
  • 4. OPD-scan
  • After LEC, surgically induced astigmatism and
    higher-order aberrations increase
  • significantly. Contrast sensitivity is
    decreased.
  • Back Ground
  • 1. The importance of quality of vision (QOV) is
    widely recognized.
  • 2. Towards the Standaridization of QOV (Quality
    of vision),the list of clinical useful
  • parameters need to be evaluated.
  • 3. Corneal astigmatism is a factor in QOV. It
    cant be predicted before surgery.

10
Conclusion 1
  • 1. Irregularity was significantly greater in the
    post-LEC group.
  • ZI may serve as a new index of postoperative
    quality of vision.
  • 2. Irregularity was significantly greater when
    corneal thickness
  • was less than 540?m.
  • Central cornea thickness may be a useful
    predictor of surgically
  • induced astigmatism.

11
Conclusion 2
  • 1. Orbscan is an effective method for evaluating
  • visual function after trabeculectomy.
  • 2. The results of this study suggest that corneal
  • thickness may have a significant effect on
    changes
  • in corneal shape after glaucoma surgery.

12
References
  • 1. Rosen WJ, Mannis MJ, Brandt JD The effect of
    trabeculectomy on corneal topography.
  • Ophthalmic Surg. 1992 Jun23(6)395-8.
  • 2. Claridge KG, Galbraith JK, Karmel V, Bates AK
    The effect of trabeculectomy on refraction,
    keratometry
  • and corneal topography. Eye. 19959 ( Pt
    3)292-8.
  • 3. Vernon SA, Zambarakji HJ, Potgieter F, Evans
    J, Chell PB Topographic and keratometric
    astigmatism up to
  • 1 year following small flap trabeculectomy
    (microtrabeculectomy). Br J Ophthalmol. 1999
    Jul83(7)779-82.
  • 4. Cunliffe IA, Dapling RB, West J, Longstaff S
    A prospective study examining the changes in
    factors that
  • affect visual acuity following
    trabeculectomy. Eye. 19926 ( Pt 6)618-22.
  • 5. Maeno A, Hayashi K, Oshika T et al Fourier
    analysis of corneal astigmatism after trabectomy.
  • Rinsho Ganka (Jpn J Clin Ophthalmol) 54(4)
    587-590. 2000
  • 6. Toyokawa N, Miyata M, Kimura H et al The
    effect of glaucoma surgery on postoperative
    visual function.
  • Rinsho Ganka (Jpn J Clin Ophthalmol) 62(4)
    461-465. 2008
  • 7. Jordan JF, Joergens S, Dinslage S, Dietlein
    TS, Krieglstein GK Central and paracentral
    corneal pachymetry
  • in patients with normal tension glaucoma and
    ocular hypertension.
  • Graefes Arch Clin Exp Ophthalmol. 2006
    Feb244(2)177-82. Epub 2005 Aug 2.
  • 8. Radford SW, Lim R, Salmon JF Comparison of
    Orbscan and ultrasound pachymetry in the
    measurement
  • of central corneal thickness. Eye. 2004
    Apr18(4)434-6.
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