Contact activation intrinsic pathway - PowerPoint PPT Presentation
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Title:
Contact activation intrinsic pathway
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... XIIa. XI Xia. IX IXa. VIIa VII. Tissue factor. Trauma. VIII. Xa. Antithrombin. VIIIa. Va. Common. pathway. X. X. Prothrombin (II) Thrombin (IIa) V. Activated ... – PowerPoint PPT presentation
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Title: Contact activation intrinsic pathway
1
Contact activation (intrinsic) pathway
Tissue factor (extrinsic) pathway
Damaged surface
Trauma
Tissue factor
XII XIIa
VIII
VIIa VII
XI Xia
Tissue factor
Trauma
IX IXa
VIIIa
Antithrombin
X
X
Xa
Common pathway
Prothrombin (II)
Thrombin (IIa)
Va
Activated Protein C
Fibrinogen (I)
Fibrin (Ia)
V
Protein S
XIIIa XIII
Protein C
Cross-linked fibrin clot
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