Developmental Biology and Biochemistry of Higher Plants and Animals

1
Developmental Biology and Biochemistry of Higher
Plants and Animals ???????? ????????? ?????????
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Dr. Danny Chamovitz ??' ??? ????????
Britannia, Room 407, Tel [phone] (lab)
03-6406703 (office) E-mail dannyc_at_tauex.tau.ac.il
www.tau.ac.il/lifesci/plant_sciences/USR/chamovi
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Our lab studies the COP9 Signalosome (CSN) in
Arabidopsis and Drosophila. We are interested in
understanding how this multi-protein complex
regulates development in such diverse organisms. 
Our results indicate that the CSN works as a
central coordinator of multiple signaling
pathways, and with a variety of other proteins,
to regulate such essential processes as light
signaling in plants and carcino-genesis in
animals. Recent publications Oron E, Mannervik
M, Rencus S, Harari-Steinberg O,
Neuman-Silberberg S, Segal D, Chamovitz DA. 2002.
COP9 signalosome subunits 4 and 5 regulate
multiple pleiotropic pathways in Drosophila
melanogaster. Development 2002 Oct129(19)4399-40
9 Yahalom A, Kim TH, Winter E, Karniol B, von
Arnim AG, Chamovitz DA. 2001.Arabidopsis eIF3e
(INT-6) associates with both eIF3c and the COP9
signalosome subunit CSN7. J. Biol Chem. 276,
334-40. 
Danny Chamovitz
Dr. Taly Yahalom, Research Associate
Graduate Students Orit Harari Efrat Oron Moshe
Dessau Nurit Levanon Tali Paz