Bipolar Depression: OlanzapineFluoxetine Combination OFC

1
Bipolar DepressionOlanzapine-Fluoxetine
Combination (OFC)
Placebo (n 355)
-2
Olanzapine (n 351)
-4
Olanzapine-fluoxetine combination (n 82)
-6
-8
Visitwise Improvement From Baseline in MADRS
(LOCF)

-10

-12



-14



-16


-18





-20
0
1
2
3
4
5
6
7
8
Week

P lt .05 vs placebo

P lt .05 vs olanzapine
Tohen MF Jr, et al. Arch Gen Psychiatry.
2003601079-1088. Erratum in Arch Gen
Psychiatry. 20046176.