Lego Mindstorms DNA Sequencing

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Lego Mindstorms DNA Sequencing

• Group E-18-C
• Christopher Young
• Bob Sherbert
• Armon Entezari
• Nick Discuillio
• James Kim
• Bryant Richardson

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Overview
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Background/Problem / Rational

• Medical Benefits of DNA sequencing
• Genome Project
• Current Methods
• (chart)
• Recent Advances

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Simulation

• The Robotic Alternative
• Macro-Level design (Small -gt Big)
• Balance becomes latching system
• Miniaturization (Big -gt Small)
• Brownian Motion
• Lithography
• Speed Factors

5
Work done toward solution of problem.Design 1

• Platform concept
• Struggles
• Height
• Parts

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Work done toward solution of problem.Design 2

• Wheel Climbing upward
• Struggles
• Elastic Tension between wheels
• Base Size
• Rigidity

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Work done toward solution of problem.Design 3

• Linear motion
• Climbs upward
• Struggles
• Unsecure claws
• Gears
• Size and Senor Placement

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Work done toward solution of problem.Design 4

• (Two claw linear climber)

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SolutionDesign 5

• (Inverted Crab)
• Technical Detail

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Costs
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Environmental

• SiO2 Used in some lithography
• Harmful on bloodstream entry
• Unknown power source
• Lego battery disposal
• (http//www.lenntech.com/Periodic-chart-elements/S
  i-en.htm)

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Recommendations for future work.

• Multiple Robots
• Transcription/Translation Monitoring
• DNA Synthesis
• Artificial Virus
• Power Source (nano-scale)
• Wireless Transmission (nano-scale)

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Summary
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Q A
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References