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The magic magnetic chair- how to facilitate best

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Start 1 week after catheter was removed (16.8=dry) ... Only active=14 and placebo=19 eligable. SUI: Active: pad test significant p=0.002 ... – PowerPoint PPT presentation

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Title: The magic magnetic chair- how to facilitate best


1
The magic magnetic chair-how to facilitate best
  • Daniela Marschall-Kehrel, Frankfurt

2
What is evidenced based medicine?
  • SUI post RPx 2 Publications
  • Mixed incontinence in both genders
  • SUI/Qol
  • IC/CPPS (females)
  • SUI in females
  • Sexual performance in women
  • CPPS/chronic prostatitis III NIDDKD

3
SUI post RPx PFMT vs MFT n105, 2 arms no cross
over
  • Start 1 week after catheter was removed
    (16.8dry). MFT 2x20weeks 30 follow-up 4 weeks,
    3, 612mo.
  • Continence
  • I 51, 64, 82
  • II 44, 50, 68
  • Pad test Ip0.004 after 12mo
  • Qol significantly better (no numbers)

4
Mixed incontinence both genders n49 24active
25placebo
  • 3x6weeks 1st intermitt. 5Hz 10, 3rest 2nd
    intermitt 50Hz 10
    follow-up 8weeks. Only active14 and placebo19
    eligable
  • SUI
  • Active pad test significant p0.002
  • Placebo worse 47 to 68
  • OAB
  • Urgency active p0.09
  • Wet active0 (21 before), placebono change
  • Pad weight
  • Active mean 2.59g p0.079
  • Placebo mean 14.67
  • Qol
  • Active p0.04
  • Placebo p0.56

5
UI 3mo post RPx n27
11active, 16placebo
  • 2x6weeks sham pat. had cross over 6wks
  • Pads/day
  • 1.41 to 0.53 62 pgt0.04
    6/9continent
  • Cross over 1.89 to 1.17
  • Incontinence episodes
  • 3.42 to 0.9173 pgt0.01
  • Pad weight
  • 4.81 to 3.81 pgt0.03
  • Cross over 5.78 to 1.5 pgt0.05
  • Qol positive trends

6
SUI-Qol women n66
  • 2x6weeks 1st 5Hz 10 2nd 50Hz 10
  • Qol
  • 53/66 80 p0.01 improved
  • Incontinece episodes 40/53 0lt0.01
  • Pad changes 46/53 plt0.01
  • 12/66 decreased Qol
  • Incontinence episodes 4/12 pgt0.05
  • Pad changes 5/12 pgt0.05
  • Urinary frequency
  • 20/33 decreased p0.002
  • 13/33 increased p missing

7
IC/CPPS treatment failures n10, investigator
initiated trial
  • 2x8weeks maximum voltage therapy
  • 9/10 improved frequency, pain, urgency
  • 3/10 total relief of symptoms but not long
    lasting
  • 1/10 failed

8
SUI females n64, follow-up 3mo n51
  • 2x6weeks
  • Incontinence
  • 18/51 34 continent
  • Pad/day
  • 1/day 16/51 32 2.5 to 1.3 p0.001
  • Leak episodes
  • 3.3 to 1.7 p0.001
  • UD
  • ALLP 43 to 48 cmH2O
  • DO 5/51 to 1/51 p0.001
  • 6 month follow-up n36
  • 10/36 28 continent
  • 8/36 22 1 pad/day

9
Orgasmic performance in women n20, 7/20 not
sexual activ
  • OAB wet questionaire(6 questions) n13
  • 6/13 no changes
  • 2/13 worse
  • 5/13 improved
  • Age was most reliable (lt55ys)

10
CPPS III NIDDKD treatment failures n21 11activ
10placebo
  • 2x4weeks 1st cont.10Hz 15 2nd
    cont.50Hz 15 follow-up 3mo and 1y
  • Pain score
  • 3mo plt0.05
  • 1y plt0.05
  • Urinary symptom score
  • 3mo plt0.05
  • 1y not significant

11
From theory to Practise
12
SUI
  • Intermitt 5-5 50 Hz 20 100 3x4-6wk
  • /- Duloxetin

13
OAB
  • Intermitt. 5-5 2Hz 20 100 3x4wk
  • Antimuscarinics?

14
CPPS/IC
  • Diclofenac 100mg Supp 10 before treatment
  • 1st intermitt. 5-5 50Hz 50 15min 3-5x4weeks
  • 2nd cont. 5Hz 100 15 see above

15
ED
  • PGE5I cont., SCAT in TF?
  • 1st intermitt.8-4 24Hz 15 3x4weeks
  • 2ndintermitt.6-3 24Hz 15 s.a.

16
SUI after RPx
  • Intermitt 5-5 50Hz 100 3-5x 4weeks
  • If OAB intermitt. 5-5 5Hz 100 3x4wks

17
CPPS/chronic Prostatitis
  • Ciproflox 200 iv 5 before start MFT and 500mg
    evening dosage if pain is dominant add
    Diclofenac 100mg Supp 10 before treatment
  • Intermitt.5-5 60Hz 55 daily 5-10 days
  • If pain cont. 5Hz 100 10/break 2/10 3-5/week

18
No personal experience
  • Fecal incontinence
  • Ogasmproblems
  • Ejaculationpower
  • Acute pain
  • Muscle volume
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