Sensitivity, Specificity and Positive predictive value - PowerPoint PPT Presentation

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Sensitivity, Specificity and Positive predictive value

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The greater the specificity, the fewer 'false positives' will be included. ... Rate of Disagreement = (False positives False negatives) / Total tested x 100 8.73 ... – PowerPoint PPT presentation

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Title: Sensitivity, Specificity and Positive predictive value


1
Sensitivity, Specificity and Positive predictive
value
2
SE, SP, PPV and NPV
  • Specificity The capacity of the test to
    correctly identify diseased individuals in a
    population TRUE POSITIVES. The greater the the
    sensitivity, the smaller the number of
    unidentified case false negatives.
  • Specificity The capacity of the test to
    correctly exclude individuals who are free of the
    disease TRUE NEGATIVES. The greater the
    specificity, the fewer false positives will be
    included.
  • Positive Predictive Value The probability of the
    disease being present,among those with positive
    diagnostic test results
  • Negative Predictive Value The probability that
    the disease was absent, among those whose
    diagnostic test results were negative.

3
Bayes Theorem
4
Example
5
  • Positivity rate or prevalence of positivity
    Total positives / Total tested x 100 49.70
  • Negativity rate or prevalenve of negativity
    Total negatives / Total tested x 100 50.30
  • Rate of Disagreement (False positives
    False negatives) / Total tested x 100 8.73
  • Rate of Agreement (True positives True
    negatives) / Total tested x 100 91.27
  • Sensitivity True positives / Total positives
    x 100 84.85
  • Specificity True negatives / Total negatives
    x 100 97.60
  • Predictive value positivity True positives /
    Tested positive x 100 97.22
  • Predictive value negativity True negatives /
    Tested negative x 100 86.70

6
Exercise 9AFuschin 0.3
7
Cont exercise 9AFuschin 1
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