Macrolide Antibiotics Bind to Ribosome - PowerPoint PPT Presentation

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Macrolide Antibiotics Bind to Ribosome

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Macrolide Antibiotics Bind to Ribosome. Macrolides Block Tunnel. Steitz: Mol. Cell 10, 117 (2002) Ribosome Macrolide Complexes. Stabilization by Aminal Formation ... – PowerPoint PPT presentation

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Title: Macrolide Antibiotics Bind to Ribosome


1
Macrolide Antibiotics Bind to Ribosome
2
Macrolides Block Tunnel
Steitz Mol. Cell 10, 117 (2002)
3
RibosomeMacrolide Complexes
4
Stabilization by Aminal Formation
5
Macrolides Differ in Effect on Protein Synthesis
6
Other Antibiotics Also Block Tunnel
Franceschi Nature 413, 814 (2001)
7
Known Resistance Mutations
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