Pharmaceutical Challenges for the Semantic Web

1
Pharmaceutical Challenges for the Semantic Web
2
Elements of Successful Drug Discovery

• Safety
• Efficacy
• Cost Effectiveness
• Timeliness

3
What Modern Drug Discovery Needs to Contend with
4
(No Transcript)
5
New Regulatory Issues Confronting Pharmaceutics
In response to the widening gap between basic
biomedical knowledge and clinical application,
governments and the academic community have
undertaken a range of initiatives. After decades
of investment in basic biomedical research, the
focus is widening to include translational
research multidisciplinary scientific
effortsdirected at "accelerating therapy
development" (i.e., moving basic discoveries into
the clinic more efficiently). from Innovation or
Stagnation, FDA Report March 2004
6
Diversity of Meanings
Genetics
Genes
Diseases
Proteins
Splice Variants
Pathways
Systems and Models
Genotypes
Active Compounds
Transcriptional Regulation