eHeart Network of Excellence

1
e-HeartNetwork of Excellence

• Claudia Riedel
• Institut fuer Biomedizinische Technik
• Universitaet Karlsruhe (TH)

2
Overview

• Motivation and Focus
• Objectives
• Placement in Framework Program
• Partners and Competences
• Actions and Integration Aspects
• Added Value
• Calendar
• Web Sites

3
e-Heart Motivation and Focus
Reconstruction of left ventricular cavity from
MRI and PET (Creatis, 2001)

• Breaking frontiers in cardio-vascular knowledge,
  physiology, pathology, diagnosis and therapy by
  personalized modeling and simulation

4
e-Heart Objectives

• Break frontiers of knowledge through
  multidisciplinary network of excellence with
  experts ranging from basic science to clinical
  groups
• Promote advanced patient specific cardio-vascular
  diagnosis, follow up and therapy
• Improve understanding of cardio-vascular
  physiology and pathology
• Get new fundamental and health knowledge from in
  silico multi-scale hybrid functional models, from
  cell to organ
• Provide a foundation for federate integrated
  projects with dedicated focus

5
Placement in Priority Thematic Areas of Research
in FP6

• 1.1.2.i Applied information technologies
  research addressing major societal and economic
  challenges
• Complex problem solving in science, engineering,
  business and for society
• Research addressing societal challenges

6
e-Heart Partners - November 2002
Academic Partners 90 Clinical Partners
11 Industry/Research
4 Industrial Partners 11 Total
116
7
University / Hospital Cardiac research - Imaging
- Signal processing - Inverse problems -
Modeling - Computer sciences -
Biomaterials Companies Imaging,
Telecommunications, Applied Mathematics,
Visualization, Consulting
8
Academic Competences

• Cardio-vascular research
• Clinical evaluation
• Signal processing and medical imaging
• Biomechanics
• Biomaterials
• Mathematical modeling
• Computer science
• Inverse problems in cardiography
• Telecommunication

9
Industrial Partners

• SMEs Vision Advance, Spain
• Scati Labs, Spain
• Técnisas Radiofisicas S. L., Spain
• MEDIS, The Netherlands
• NAG Ltd, UK
• Apteryx, France
• Théralys, France
• Ultimed, France
• Intellimed, France
• Big companies ESI Group, France
• CETIR, Spain
• Philips Research France
• France Télécom RD

10
European Common Actions

• Create a platform of in silico mathematical,
  numerical models and modeling tools
• Test models and modeling tools on huge patients
  populations from selected clinical sites
• Share acquisition devices, e.g. small animal
  imaging platforms, european synchrotron, positron
  emission cameras
• Benefit from next generation ultra high
  performance computing resources Health Grid

11
(No Transcript)
12
e-Heart Integration Aspects

• Identification of expertise
• Excellence and know how
• Overlap and gaps
• Sharing resources
• Acquisition devices and computing facilities
  (GRID)
• Software tools and expertise
• Data bases
• Defining standards
• Man machine interfaces
• Data formats
• Platform independence (from PC to GRID)
• Documentation

13
Sharing Imaging Resources
Metabolism PET, SPECT
Perfusion MRI, PET, US
Contraction MRI, US
RV
LV
Cutting plane
14
Integration Aspects - Research Activities in
Common

• Exchange students between labs and clinical sites
• Provide high level Master and Ph.D. courses
• Develop collaborative projects on overlapping
  topics
• Create multidisciplinary research groups, e.g.
  with engineers, physicians and computer
  scientists
• Promote new research activities to fill gaps

15
Added Value - European Scientists

• Solve new classes of problems
• Increase general knowledge level by easy access
  to data and minds
• Decrease research costs by decreasing redundant
  actions
• Increase speed for producing new generation in
  silico models
• Provide large scale remote access to validated
  software

16
Added Value for Radiologists, Cardiologists and
Heart Surgeons

• Facilitates consensus between medical experts
• Decrease costs of research, diagnosis and therapy
  of cardiac diseases
• Make clinical validation more efficient
• Provide validated models and modeling software,
  e.g. for
• simplified quantification of cardiac function
• forehand planning of therapeutic interventions

17
Added Value for Patients

• Best up-to-date diagnosis (know how, validated
  interpretation, improved software tools)
• Validated therapeutic protocols (medical
  consensus, guidelines)
• Less risk for medical errors (experts are
  identified)

18
Added Value for European Industry

• Imaging system companies
• Radiology service providers
• Image analysis and visualization companies
• High performance computing industry
• Pharmaceutical industry
• Contrast media industry
• Medical devices industry
• surgical
• prosthetic
• electrocardiological

19
e-Heart Calendar

• 8-9 July 2002 First meeting, Zarogoza
• 3-4 October 2002 Second meeting, Lyon
• 4-8 December 2002 EMBEC Forum, Vienna
• 15 January 2003 Core group meeting, Lyon
• 16-17 January 2003 HealthGrid meeting, Lyon
• March 2003 Proposal to EC
• 5-6 June 2003 FIMH 03 Meeting, Lyon
• FIMH 05 in Spain ?

20
e-Heart Web Addresses

• e-Heart http//www.creatis.insa-lyon.fr/e-Heart/
• FIMH Conferencehttp//www.creatis.insa-lyon.fr/FI
  MH/
• HealthGrid Conferencehttp//lyon2003.healthgrid.o
  rg/