How Microfluidics Hepls To Achieve Deagglomeration?

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How Microfluidics Hepls To Achieve
Deagglomeration?
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Deagglomeration is the process of reducing the
size of loosely bound clusters (agglomerates) of
powders or crystals without causing any further
fragmentation of the individual particles
themselves. This process is critical to ensuring
a more uniform formulation in applications where
one material is being dispersed or mixed with
another.
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Different Methods of Deagglomeration There are
two main methods of deagglomeration dry milling
and wet milling. Wet milling is often the
preferred technique because it offers greater
precision, protects delicate particles, and
operates more efficiently. In wet milling, a
liquid medium is added to the material, which
helps break apart clumps by reducing surface
tension and utilising mechanical inertia. Wet
milling is the preferred process, as it allows
for more precision and speed while protecting
more fragile particles at the same time.
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The Procedure of Deagglomeration Deagglomeration
is a process that tackles the issue of solid
materials, like powders, or solid/liquid blends,
such as slurries, clumping together and forming
lumps. These agglomerates can cause various
problems in a product, including uneven settling
and the production of lower-quality results.
Additionally, they can create undesirable
textures in products that should be smooth and
free from lumps. Not just that, but
Deagglomeration also eliminates safety issues for
pharmaceutical applications and poor coverage and
inconsistent viscosity for paints and inks.
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• Advantages of the Deagglomeration Process
• There are several advantages to using
  deagglomeration.Ensuring a more uniform
  formulation in applications where one material is
  being dispersed or mixed together
• Preventing settling to eliminate a less uniform
  and lower-quality product
• Avoiding undesirable textures for products that
  are meant to be completely smooth and lump-free
• Addressing safety issues for applications such as
  pharmaceutical products
• Improving coverage and consistent viscosity for
  materials such as paints and inks

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Which Industries Use the Deagglomeration
Process? Deagglomeration is a critical part of
the dispersion process. It helps to ensure a more
uniform formulation in applications where one
material is being dispersed or mixed with
another. The industries that use the
deagglomeration process include personal care,
pharmaceutical, food and beverage, chemical, and
cannabis processing. How does Deagglomeration
Work in the pharmaceutical industry?
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Deagglomeration plays a crucial role in the
dispersion process within the pharmaceutical
industry. It helps achieve a uniform formulation
when combining or mixing different materials.
This process specifically addresses the issue of
solid materials, like powders, or solid/liquid
blends, such as slurries, clumping together and
forming lumps. How Does IDEX Enable the
Deagglomeration Process for Industries? IDEX
provides Microfluidizer Processors that deliver
exceptional outcomes in producing uniform
nanoemulsions, disrupting cells, and achieving
consistent particle size reduction.
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These machines consistently surpass expectations
by achieving substantial reductions in particle
size and remarkably uniform particle size
distributions. The exceptional efficiency of this
technology is attributed to the unique design of
their exclusive fixed-geometry Interaction
Chamber. The ability to precisely control the
shearing level grants customers the flexibility
to accomplish particle size reduction goals using
less energy.
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Conclusion Deagglomeration is an important
process that offers several advantages over other
methods. It allows for better flow properties,
improved compressibility, better content
uniformity, an improved dissolution rate of
poorly soluble drugs, reduced dust levels during
the manufacturing process, reduced air
entrapment, and increased powder compressibility.
Microfluidics by IDEX offers equipment for
deagglomeration that is technologically superior
and optimised to meet customer needs.
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