PATHOLOGY PRACTICAL

1
Q.1

• The following biochemical results were recorded
  in a 29 year
• old female who attended her General Practitioner
• complaining of tiredness, weight loss, heat
  intolerance and
• increased bowel movements.
• Patient Results Reference
  Range
• Total T4 196 nmol/L
  (5-11.5)
• TSH lt0.01IU/L
  (0.7-7.0)
• Questions
• (a) What is your diagnosis?
• (b) Mention two physical findings that might be
  present in this patient?
• (c) Mention two other tests that might be
  abnormal in this patient?

2
Q.2

• A 35-year old lady gives history of increasing
  headaches
• and progressive blindness. Her blood pressure
• is found to be 210/135. Blood sample was taken.
  The
• following are her biochemical findings
• Pat. Values Ref. values
• Sodium 130mmol/L (135-145)
• Potassium. 3.1mmol/L (3.0- 6-5)
• HC03 10mmol/L (22-30)
• Creatinine 400µmol/L (60-120)
• Questions
• Indicate all abnormal biochemical abnormalities
  in this patient?
• What is your diagnosis
• What is the acid base disorder in this patient

3
Q.3

• The results shown are from a 61 year old patient
• referred for endocrinology testing because of
  long
• standing complaints of intractable headaches.
• PATIENT REF. RANGE
• TSH 0.02 mIU/L lt 0.04 T 3
  125 MMOL/L 94-170
• Free T4 0.9 MMOL/L
  0.1.8Prolactin 57.5 MMOL/L 2-14
• 1.Suggest the Diagnosis
• 2. What other clinical complaint may be present
  in this patient

4
Q.4

• A 65 years old retired army officer presents
• to hospital complaining of swollen legs (Lower
• limb edema).
• Laboratory evaluation of his problem shows the
• following serum biochemical values
• Patient
  Reference Range
• Creatinine 345umol/L 60-120
• Parathyroid Hormone 1650 mmol/L lt 70
• 1. What is the primary problem of this patient ?
• 2. Mention the complication that is revealed by
  the
• levels of Parathyroid hormone in this patient
  ?

5
Q.5

• Section of from A 45 years old Euthyroid female
  with an anterior neck swelling.
• I. Diagnosis is (choose one)
• Adenocarcinoma
• Hashimoto thyroiditis
• Nodular goiter
• Follicular carcinoma
• Hyperthyroidism
• II. Give the Cause
• ..

6
Q.6

• The patient to the left had emotional
  instability, weight loss in spite of good
  appetite and fine tremors.
• 1.Mention 3 gross pathological features
• 2.What is the most likely diagnosis
• 3.Mention 3 serum biochemical anomalies which
  would help to confirm the diagnosis
• 4. Mention ONE most common and consistent
  autoantibody assosiated with this disease

7
Q.7

• a)This cell change is characteristic in which of
  theinflammatory thyroid disease?
• b) What is the name of the cell change
• c) The name of the cells which have gone this
  cell change are known as --------------

8
Q.9

• The patient to the left had hypersecretion of an
  adrenal gland lesion
• Name the 3 prominent physical features
• ii) What is the name of the substance secreted
• (iii) What general name is given to this
  condition

9
QN 10.

• OBSERVE THE PICTURE
• A. state what is the organ shown?
• B. Name 1 gross morphologic feature common in
  both A-71-62 and A-71-63 below.
• C. What is the difference in the gross feature
  you have named above?
• D. Name the likely causal argents in relation to
  A-71-62 and A-71-63 below.

10
Q.11

• This is gastrectomy specimen
• Describe 2 gross features see
• B. What is the diagnosis
• C. List 3 complications of the condition named in
  your diagnosis B above.

11
THE END