Adherent Lentivirus Suspension Production & Manufacturing

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Adherent Lentivirus Suspension Production
Manufacturing
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• GenScript ProBio is the world's leading biotech
  company founded in 2002 in New Jersey USA. We at
  GenScript ProBio provide various solutions based
  on gene synthesis technology including lentivirus
  manufacturing, CAR-T IND filing, plasmid
  manufacturing production, and many more. 
• GenScript ProBio has also established integrated
  innovative biologics CDMO platforms that cover
  all your needs from the pre-clinical to clinical
  phases. We offer flexible and best-quality
  lentiviral vector production services to cover
  all your needs from the pre-clinical to clinical
  phases.

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One-Stop Solutions We Provide
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Cell Banking

• GenScript ProBio offers cell bank manufacturing
  services to customers. We ensure that our
  Lentivirus production is fully compliant with GMP
  and with full characterization. 
• Our cell banks support customers projects moving
  forward smoothly from the clinical phase to
  commercialization.
• We also have our own cell banks ready for
  lentiviral vector production
• MCB/WCB Construction
• Cell Bank Characterization
• Cell Bank Stability Test

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Process Development (PD)

• We have a developed adherent as well as
  suspension culture system in a dedicated PD lab.
  We are experienced in developing and providing
  successful deliveries over the past year which
  has enabled us to reduce the development cycle
  and streamline processes.
• Upstream Process Development
• Downstream Process Development
• Small Scale Production

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Analytical Development (AD)

• At GenScript ProBio, we offer a wide range of
  assays, which have been developed and optimized,
  to ensure quality lentiviral products. 
• The analytical support for customers includes
  analytical development, qualification, validation
  and transfer, which is also essential in CMC
  study for regulatory filings.
• GenScript ProBio also develops assays tailored
  to customers requirements for specific
  applications or types of products.
• Analytical Method Development
• Analytical Method Qualification

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Lentiviral Vector Production

• We are experienced in the manufacturing of
  lentiviral vectors adopting both adherent
  lentivirus production and suspension systems,
  providing customers with quality products for
  preclinical, clinical and commercial supply.

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Manufacturing with an adherent system

• The largest manufacturing scale is 75CF10
• High final product titer of 5E7 TU/m

Manufacturing with the suspension system

• up to 200L manufacturing scale
• Proprietary cell line PowerSTM-293T
• Yield improves 45 times compared with another
  commercial cell line
• 50 material cost reduction

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Stability Test

• GenScript ProBio provides influencing factors
  and accelerated and long-term stability studies
  according to ICH guidelines to monitor product
  integrity over time. 
• Accelerated Stability Test
• Influencing Factor Stability Test
• Long-term Stability Test

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Thank You

• Website www.genscriptprobio.com
• Email cdmo.us_at_genscript.com
• Call Us 17328859188 18774367274