what is orthobiologics?

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What is orthobiologics?
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• Orthobiologics is a part of regenerative
  medicine, which uses natural substances, or
  biologics, from ones own body as an attempt to
  treat musculoskeletal injuries, tendon injuries,
  muscle injuries, (and) osteoarthritis, said
  Facile.
• Regenerative medicine is an area of medicine
  that utilizes cells to treat, repair, or regrow
  organ tissues. While its not understood what
  these cells are doing, its believed that they
  are repairing and decreasing inflammation, which
  can then improve the repair process in a
  particular injury, she explained.

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Tissue types of orthobiologics

• There are four different types of tissues that
  constitute orthobiologics, and they are comprised
  of the following
• Blood-derived
• Extra-cellular matrix
• Conditioned media
• Stem cells

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Who could benefit from orthobiologics?

• Facile says this is one of the most challenging
  parts of orthobiologics, because theres still so
  much to learn.
• The potential is there for many musculoskeletal
  conditions, but we lack high quality studies to
  guide our decision making.
• Because of this, one needs to speak with a
  trained care provider like Dr. Herman, said
  Facile.
• Thats ultimately a provider and patients
  decision to determine benefits, through shared
  decision-making, education and information.
• We cannot replace surgical interventions.
• This is an offering for those that may not want
  surgery, or may not qualify for surgery to give
  them an opportunity to get their quality of life
  back.

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So, what are the differences?

• Donella Herman, M.D. is a sports medicine
  specialist at Sanford Orthopedics and Sports
  Medicine in Sioux Falls, South Dakota.
• She said orthobiologics could be considered
  narrow, as opposed to the broad scope of
  regenerative medicine.
• In orthobiologics, we focus on using platelet
  rich plasma and therapeutic cells.For
  regenerative medicine, theyre doing things like
  growing cells, utilizing other peoples cells to
  fight cancer.
• Its a broader term, and a broader thing, said
  Dr. Herman.
• She, Facile, and others on the team at Sanford
  have narrowed their therapies to specifically
  platelet rich plasma and therapeutic cells, in an
  attempt to treat musculoskeletal injuries.
• Dr. Herman said the cells they use are derived
  from either bone or adipose tissue.
• Meaning, they use cells from a patients bone, or
  an area on their body with more fat.
• Those areas are rich in regenerative cells,
  including stem cells.

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References

• https//news.sanfordhealth.org/orthopedics/what-is
  -orthobiologics/textE2809COrthobiologics2
  0is20a20part20of,)20osteoarthritis2CE2809D
  20said20Facile.
• https//www.orthobiotexas.com/blog/httpswwworthobi
  otexascomblogwhat-is-the-science-of-orthobiologics
  -26978.html