Immunotech : The Systemic Enzyme Based Immunomodulator in Poultry

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IF IMMUNITY IS YOUR TO P PRIORITY...
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INTRODUCTION
Immune system plays pivotal role in ?ghting
against pathogenic microbes thereby helps in
maintaining overall health and well-being of bird.
Similarly, the Infectious bursal disease (IBD),
chicken infectious anemia (CIA), and Marek's
disease (MD) are major infectious diseases that
increase susceptibility to viral, bacterial, and
parasitic diseases and interfere with adaptive
vaccinalimmunity.


The primary role of the immune system is to
recognize foreign organisms that have managed to
enter the system and initiate appropriate
physiological responses to neutralizeoreliminateth
em.

In general the control measures for tackling the
avian immunosuppression rely largely on
minimizing stress, reducing exposure to
infectious agents through biosecurity, and
increasing host resistance to infectious immunosup
pressive diseases byimmunomodulation. Thus a
well-balanced immune system improved intestinal
functionis correlated with
The avian immune system have both non-speci?c
and speci?c defence mechanisms to ?ght against
infectious agentswhichincludes

1. Innate(nonspeci?c)immunity
2. Adaptive(speci?c)immunity
1. Productionperformance
Animals in a production environment can be
exposed to stressors and infectious diseases that
impair innate and adaptive immunity, erode
general health and welfare, and diminish genetic
and nutritional potential for ef?cientproduction.

2. Health wellness
3. Food safety
Innate immunity can be affected by stressful
physiologic events related to hatching and to
environmental factors during the ?rst week of
life. Exposure to environmental ammonia,
foodborne mycotoxins, and suboptimal nutritioncand
iminish innateimmunity.
Disease Condition (with Normal Body Cells)
()
Presenting Surface Antigens
()
(-)
Innate linked immunity
Adaptive immunity
IMMUNE PROCESS (Body Defense Mechanism)
Virus
Broad
Speci?c
() Lymphocyte-B
Controls spread
clears infection
Directs adaptive response
Elicits a memory response
()
Bacterium
()
Memory Cells
hours-days
days-weeks
Ag-Ab Reaction
Speci?c Antibodies Production
ABOUT IMMUNOTECH
With the growing pressures on the livestock
farming industry, there is great need for
innovative solutions that can help boost the
animals' immune system, reduce stress
and in?ammation leading to animal health and
effective production.

Immunotech

Immunotech is a unique systemic enzyme
based Immunomodulator in poultry which comprises
a synergistic combination of Serratiopeptidase,
Nattokinase, Bromelain, Papain Bio?avonoid
(Rutin).

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MODE OF ACTION
Immunotech increases the serum levels of
systemic enzymes, which activates
a-2-macroglobulin - a serum protein that
facilitates the binding and removal of foreign
peptides, excessive in?ammatory mediators
and auto-toxic endogenous proteins and thereby
support balanced humoral and cell-mediated immune
function andmodulatesystemic in?ammation.
Immunotech hydrolyses bradykinin, histamine,
and serotonin responsible forin?ammation due to
infection.


Immunotech reduces the impact of disease stress
and its secondary complications by targeting the
circulating immune complexes from the blood,
degrading the toxins and facilitating their
removal from the system via phagocytes.
Immunotech binds to a-2-macroglobulin in the
blood in the ratio of 11, which helps to mask
its antigenicity but retain its enzymatic
activity. It is slowly transferred to site of
infection.

a-2 macroglobulin Activation (Complex
Formation) Binding of the Complex to In?ammatory
Mediators Clearance of a-2M-Protease-MI Complexes
from Circulation
E
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E E
E
E
E E
E
E
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IMMUNOTECH TRIAL
Field based research trial was conducted to
evaluate impact of Immunotech supplementation on
bird performance. For this trial, a straight run
?ock of 400 Cobb 400Y broiler chickens
were distributed into 2 treatment groups. Each
treatment group had 20 replicate pens and there
were 10 birds in each pen (n 200 pergroup).
Parameter
Control 2.621 1.67
Immunotech 2.636
Body Weight Gain (Kg) FCR
1.63
Mortality()
11
1.5
Vaccine titre against ND at different ages
11
2.4 2.35 2.3
1.5
2.25 2.2
Control 2.621
Immunotech 2.636
2.15
12-d
28-d
40-d Immunotech
Control
Vaccine titre against IBD at different ages
4 3.5 3
Control 1.67
Immunotech 1.63
2.5 2
1.5 1
0.5 0
12-d
28-d
40-d Immunotech
Control
Immunotech
Control
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IMMUNOTECH A VERSATILE SOLUTION
PRODUCT SPECIFICATION
Recommended Inclusion Levels
Continuous Application (Low-Risk Condition)
Recommended as a preventive measure to stimulate
the Immunomodulation process and the overall
Immune function.
Dosage for continuous application 250 ml/ 1000
birds in drinking water twice a day for ?rst two
days of application, followed by 100ml/ 1000
birds twice a day third day onwards.
Immunotech

IntermittentApplication (High-Risk Condition)
It is ?exible and recommended to identify stress
periods withprecision.
Stress conditions (Disease outbreaks,heatshock) Ne
wlyhatchedchicks from day 1 to day 3

24 h after post-antibiotic therapy for three days
Dosage for intermittent application 250 ml/ 1000
birds in drinking watertwice a day.
BENEFITS
BROILER
PRESENTATION
Body Weight Gain Processing Yields Feed Ef?ciency

Immunotech Liquid 1,5 Lit. Immunotech Powder
1 Kg
Higher Vaccine Titre
LAYER
Egg Production

Egg Quality
Feed Ef?ciency Higher Vaccine Titre
BREEDER
Egg Production

Fertility Hatchability Chick Quality
Performance Immunity
Advanced Bio-Agro Tech Limited (ABTL)
Corporate Of?ce
Registered Of?ce
No. 201, 2nd Floor, S.N.6/1/1, Deron Hills, Baner
Road, Pune 411045 (India)
5th Floor Sun Magnetica, LIC Service Road,
Louiswadi, Thane (W) 400604 (India)
91 20 2729 1020 / 21
www.abtlenzymes.com
info_at_abtl.in
CIN U24100MH2004PLC149464